Reaction: dihydrochelirubine + [reduced NADPHhemoprotein reductase] + O2 = 12-hydroxydihydrochelirubine + [oxidized NADPHhemoprotein reductase] + H2O
For diagram of reaction click here.
Other name(s): dihydrochelirubine 12-hydroxylase
Systematic name: dihydrochelirubine,[reduced NADPHhemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
Comments: A cytochrome P-450 (heme-thiolate) protein from the plant Thalictrum bulgaricum.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Kammerer, L., De-Eknamkul, W. and Zenk, M.H. Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine in dihydromacarpine formation by Thalictrum bulgaricum. Phytochemistry 36 (1994) 1409-1416.