IUBMB Enzyme Nomenclature


Accepted name: geranylgeraniol 18-hydroxylase

Reaction: geranylgeraniol + [reduced NADPH—hemoprotein reductase] + O2 = 18-hydroxygeranylgeraniol + [oxidized NADPH—hemoprotein reductase] + H2O

For diagram of reaction click here.

Glossary: plaunotol = 18-hydroxygeranylgeraniol

Other name(s): GGOH-18-hydroxylase

Systematic name: geranylgeraniol,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (18-hydroxylating)

Comments: A cytochrome P-450 (heme-thiolate) protein isolated from the plant Croton sublyratus.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Tansakul, P. and De-Eknamkul, W. Geranylgeraniol-18-hydroxylase: the last enzyme in the plaunotol biosynthetic pathway in Croton sublyratus. Phytochemistry 47 (1998) 1241-1246.

[EC created 2009 as EC, transferred 2018 to EC]

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