IUBMB Enzyme Nomenclature


Accepted name: salviol synthase

Reaction: ferruginol + [reduced NADPH—hemoprotein reductase] + O2 = salviol + [oxidized NADPH—hemoprotein reductase] + H2O

For diagram of reaction click here.

Glossary: salviol = abieta-8,11,13-triene-2α,12-diol

Other name(s): CYP71BE52

Systematic name: ferruginol,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (salviol forming)

Comments: A cytochrome P-450 (heme-thiolate) protein isolated from the plant Salvia pomifera (apple sage).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Ignea, C., Athanasakoglou, A., Ioannou, E., Georgantea, P., Trikka, F.A., Loupassaki, S., Roussis, V., Makris, A.M. and Kampranis, S.C. Carnosic acid biosynthesis elucidated by a synthetic biology platform. Proc. Natl Acad. Sci. USA 113 (2016) 3681-3686. [PMID: 26976595]

[EC created 2018]

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