IUBMB Enzyme Nomenclature

EC 1.14.99.2

Accepted name: kynurenine 7,8-hydroxylase

Reaction: kynurenate + reduced acceptor + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor

Other name(s): kynurenic acid hydroxylase; kynurenic hydroxylase; kynurenate 7,8-hydroxylase

Systematic name: kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9029-63-4

References:

1. Taniuchi, H. and Hayaishi, O. Studies on the metabolism of kynurenic acid. III. Enzymatic formation of 7,8-dihydroxykynurenic acid. J. Biol. Chem. 238 (1963) 283-293.

[EC 1.14.99.2 created 1965 as EC 1.14.1.4, transferred 1972 to EC 1.14.99.2]


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