IUBMB Enzyme Nomenclature

EC 1.14.99.26

Accepted name: 2-hydroxypyridine 5-monooxygenase

Reaction: 2-hydroxypyridine + reduced acceptor + O2 = 2,5-dihydroxypyridine + acceptor + H2O

Other name(s): 2-hydroxypyridine oxygenase

Systematic name: 2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating)

Comments: Also oxidizes 2,5-dihydroxypyridine, but does not act on 3-hydroxypyridine, 4-hydroxypyridine or 2,6-dihydroxypyridine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 96779-45-2

References:

1. Sharma, M.L., Kaul, S.M. and Shukla, O.P. Metabolism of 2-hydroxypyridine by Bacillus brevis (INA). Biol. Membr. 9 (1984) 43-52.

[EC 1.14.99.26 created 1989]


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