IUBMB Enzyme Nomenclature

EC 1.14.99.35

Accepted name: thiophene-2-carbonyl-CoA monooxygenase

Reaction: thiophene-2-carbonyl-CoA + reduced acceptor + O2 = 5-hydroxythiophene-2-carbonyl-CoA + acceptor + H2O

Other name(s): thiophene-2-carboxyl-CoA dehydrogenase; thiophene-2-carboxyl-CoA hydroxylase; thiophene-2-carboxyl-CoA monooxygenase

Systematic name: thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase

Comments: A molybdenum enzyme. Highly specific for thiophene-2-carbonyl-CoA. Tetrazolium salts can act as electron acceptors.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 208540-44-7

References:

1. Bambauer, A., Rainey, F.A., Stackebrandt, E. and Winter, J. Characterization of Aquamicrobium defluvii gen. nov. sp. nov., a thiophene-2-carboxylate-metabolizing bacterium from activated sludge. Arch. Microbiol. 169 (1998) 293-302. [PMID: 9531630]

[EC 1.14.99.35 created 2000]


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