IUBMB Enzyme Nomenclature

EC 1.17.1.10

Accepted name: formate dehydrogenase (NADP+)

Reaction: formate + NADP+ = CO2 + NADPH

Other name(s): NADP+-dependent formate dehydrogenase

Systematic name: formate:NADP+ oxidoreductase

Comments: A tungsten-selenium-iron protein characterized from the bacterium Moorella thermoacetica. It is extremely sensitive to oxygen.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, CAS registry number:

References:

1. Andreesen, J.R. and Ljungdahl, L.G. Nicotinamide adenine dinucleotide phosphate-dependent formate dehydrogenase from Clostridium thermoaceticum: purification and properties. J. Bacteriol. 120 (1974) 6-14. [PMID: 4154039]

2. Yamamoto, I., Saiki, T., Liu, S.-M. and Ljungdahl, L.G. Purification and properties of NADP-dependent formate dehydrogenase from Clostridium thermoaceticum, a tungsten-selenium-iron protein. J. Biol. Chem. 258 (1983) 1826-1832. [PMID: 6822536]

[EC 1.17.1.10 created 1978 as EC 1.2.1.43, transferred 2017 to EC 1.17.1.10]


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