Reaction: 4-oxocyclohexane-1-carboxylate + O2 = 4-oxocyclohex-2-ene-1-carboxylate + H2O2
Glossary: 4-oxocyclohexane-1-carboxylate = 4-oxocyclohexanecarboxylate
Other name(s): chcC1 (gene name); 4-oxocyclohexanecarboxylate desaturase I; 4-oxocyclohexanecarboxylate 2-desaturase
Systematic name: 4-oxocyclohexane-1-carboxylate:oxygen oxidoreductase (4-oxocyclohex-2-ene-1-carboxylate-forming)
Comments: Contains FAD. The enzyme, characterized from the bacterium Corynebacterium cyclohexanicum, participates in a cyclohexane-1-carboxylate degradation pathway.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Kaneda, T., Obata, H. and Tokumoto, M. Aromatization of 4-oxocyclohexanecarboxylic acid to 4-hydroxybenzoic acid by two distinctive desaturases from Corynebacterium cyclohexanicum. Properties of two desaturases. Eur. J. Biochem. 218 (1993) 997-1003. [PMID: 8281951]
2. Yamamoto, T., Hasegawa, Y., Lau, P.CK. and Iwaki, H. Identification and characterization of a chc gene cluster responsible for the aromatization pathway of cyclohexanecarboxylate degradation in Sinomonas cyclohexanicum ATCC 51369. J. Biosci. Bioeng. 132 (2021) 621-629. [PMID: 34583900]