IUBMB Enzyme Nomenclature


Accepted name: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)

Reaction: D-glyceraldehyde 3-phosphate + phosphate + NADP+ = 3-phospho-D-glyceroyl phosphate + NADPH + H+

For diagram of reaction click here, another presentation click here.

Other name(s): triosephosphate dehydrogenase (NADP); dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating); glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating); NADP-glyceraldehyde-3-phosphate dehydrogenase; NADP-glyceraldehyde phosphate dehydrogenase; NADP-dependent glyceraldehyde phosphate dehydrogenase; NADP-triose phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase (NADP) (phosphorylating); GAPDH

Systematic name: D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37250-87-6


1. Brenneman, F.N. and Volk, W.A. Glyceraldehyde phosphate dehydrogenase activity with triphosphopyridine nucleotide and with diphosphopyridine nucleotide. J. Biol. Chem. 234 (1959) 2443-2447.

2. Gibbs, M. TPN triosephosphate dehydrogenase from plant tissue. Methods Enzymol. 1 (1955) 411-415.

3. Rosenberg, L.L. and Arnon, D.I. The preparation and properties of a new glyceraldehyde-3-phosphate dehydrogenase from photosynthetic tissues. J. Biol. Chem. 217 (1955) 361-371.

[EC created 1961]

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