IUBMB Enzyme Nomenclature


Accepted name: (R)-dehydropantoate dehydrogenase

Reaction: (R)-4-dehydropantoate + NAD+ + H2O = (R)-3,3-dimethylmalate + NADH + 2 H+

For diagram of reaction click here.

Other name(s): D-aldopantoate dehydrogenase; D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase

Systematic name: (R)-4-dehydropantoate:NAD+ 4-oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37250-96-7


1. Magee, P.T. and Snell, E.E. The bacterial degradation of pantothenic acid. IV. Enzymatic conversion of aldopantoate to α-ketoisovalerate. Biochemistry 5 (1966) 409-416. [PMID: 4287371]

[EC created 1972]

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