IUBMB Enzyme Nomenclature

EC 1.2.1.4

Accepted name: aldehyde dehydrogenase (NADP)

Reaction: an aldehyde + NADP+ + H2O = a carboxylate + NADPH + H+

Other name(s): NADP-acetaldehyde dehydrogenase; NADP-dependent aldehyde dehydrogenase; aldehyde dehydrogenase (NADP)

Systematic name: aldehyde:NADP+ oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, PDB, CAS registry number: 9028-87-9

References:

1. Adachi, O., Matsushita, K., Shinagawa, E. and Ameyama, M. Crystallization and properties of NADP-dependent aldehyde dehydrogenase from Gluconobacter melanogenus. Agric. Biol. Chem. 44 (1980) 155-164.

2. Jakoby, W.B. Aldehyde dehydrogenases. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 203-221.

3. Nakayama, T. Acetic acid bacteria. II. Intracellular distribution of enzymes related to acetic acid fermentation, and some properties of a highly purified triphosphopyridine nucleotide (TPN)-dependent aldehyde dehydrogenase. J. Biochem. (Tokyo) 48 (1960) 812-830.

4. Seegmiller, J.E. Triphosphopyridine nucleotide-linked aldehyde dehydrogenase from yeast. J. Biol. Chem. 201 (1953) 629-637.

[EC 1.2.1.4 created 1961]


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