IUBMB Enzyme Nomenclature


Accepted name: glutamate-5-semialdehyde dehydrogenase

Reaction: L-glutamate 5-semialdehyde + phosphate + NADP+ = L-glutamyl 5-phosphate + NADPH + H+

For diagram click here.

Other name(s): β-glutamylphosphate reductase; γ-glutamyl phosphate reductase; β-glutamylphosphate reductase; glutamate semialdehyde dehydrogenase; glutamate-γ-semialdehyde dehydrogenase

Systematic name: L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 54596-29-1


1. Baich, A. The biosynthesis of proline in Escherichia coli: phosphate-dependent glutamate-semialdehyde dehydrogenase (NADP), the second enzyme in the pathway. Biochim. Biophys. Acta 244 (1971) 129-134. [PMID: 4399189]

[EC created 1976]

Return to EC 1.2.1 home page
Return to EC 1.2 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page