Reaction: a long-chain aldehyde + NAD+ + H2O = a long-chain carboxylate + NADH + 2 H+
Other name(s): long-chain aliphatic aldehyde dehydrogenase; long-chain fatty aldehyde dehydrogenase; fatty aldehyde:NAD+ oxidoreductase
Systematic name: long-chain-aldehyde:NAD+ oxidoreductase
Comments: The best substrate is dodecylaldehyde.
Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, CAS registry number: 59298-89-4
References:
1. Le Beault, J.M., Roche, B., Duvnjak, Z. and Azoulay, E. Alcool- et aldéhyde-déshydrogénases particulaires de Candida tropicalis cultivé sur hydrocarbures. Biochim. Biophys. Acta 220 (1970) 373-385. [PMID: 5499619]
2. Moreau, R.A. and Huang, A.H.C. Oxidation of fatty alcohol in the cotyledons of jojoba seedlings. Arch. Biochem. Biophys. 194 (1979) 422-430. [PMID: 36040]
3. Moreau, R.A. and Huang, A.H.C. Enzymes of wax ester catabolism in jojoba. Methods Enzymol. 71 (1981) 804-813.