Reaction: an aldehyde + NAD(P)+ + H2O = a carboxylate + NAD(P)H + H+
Other name(s): aldehyde dehydrogenase [NAD(P)]; ALDH
Systematic name: aldehyde:NAD(P)+ oxidoreductase
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9028-88-0
References:
1. Black, S. Yeast aldehyde dehydrogenase. Arch. Biochem. Biophys. 34 (1951) 86-97.
2. Jakoby, W.B. Aldehyde dehydrogenases. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 203-221.
3. King, T.E. and Cheldelin, V.H. Oxidation of acetaldehyde by Aerobacter suboxydans. J. Biol. Chem. 220 (1956) 177-191.
4. Steinman, C.R. and Jakoby, W.B. Yeast aldehyde dehydrogenase. I. Purification and crystallization. J. Biol. Chem. 242 (1967) 5019-5023. [PMID: 4293780]
5. Tanenbaum, S.W. The metabolism of Acetobacter peroxidans. I. Oxidative enzymes. Biochim. Biophys. Acta 21 (1956) 335-342.