IUBMB Enzyme Nomenclature


Accepted name: sulfoacetaldehyde dehydrogenase (acylating)

Reaction: 2-sulfoacetaldehyde + CoA + NADP+ = sulfoacetyl-CoA + NADPH + H+

Glossary: 2-sulfoacetaldehyde = 2-oxoethanesulfonate

Other name(s): SauS

Systematic name: 2-sulfoacetaldehyde:NADP+ oxidoreductase (CoA-acetylating)

Comments: The enzyme is involved in degradation of sulfoacetate. In this pathway the reaction is catalysed in the reverse direction. The enzyme is specific for sulfoacetaldehyde and NADP+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Weinitschke, S., Hollemeyer, K., Kusian, B., Bowien, B., Smits, T.H. and Cook, A.M. Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16. J. Biol. Chem. 285 (2010) 35249-35254. [PMID: 20693281]

[EC created 2011]

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