Reaction: 4'-apo-β,ψ-caroten-4'-al + NAD+ + H2O = neurosporaxanthin + NADH + 2 H+
For diagram of reaction, click here
Glossary: neurosporaxanthin = 4'-apo-β,ψ-caroten-4'-oic acid
Other name(s): β-apo-4'-carotenal oxygenase; YLO-1; carD (gene name)
Systematic name: 4'-apo-β,ψ-carotenal:NAD+ oxidoreductase
Comments: Neurosporaxanthin is responsible for the orange color of of Neurospora.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Estrada, A.F., Youssar, L., Scherzinger, D., Al-Babili, S. and Avalos, J. The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway. Mol. Microbiol. 69 (2008) 1207-1220. [PMID: 18627463]
2. Diaz-Sanchez, V., Estrada, A.F., Trautmann, D., Al-Babili, S. and Avalos, J. The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi. FEBS J. 278 (2011) 3164-3176. [PMID: 21749649]