EC 1.2.1.97

Reaction: (2S)-3-sulfolactaldehyde + NAD(P)⁺ + H₂O = (2S)-3-sulfolactate + NAD(P)H + H⁺

For diagram of reaction click here.

Glossary: (2S)-3-sulfolactaldehyde = (2)-2-hydroxy-3-oxopropane-1-sulfonate

Other name(s): SLA dehydrogenase

Systematic name: (2S)-3-sulfolactaldehyde:NAD(P)⁺ oxidoreductase

Comments: The enzyme, characterized from the bacterium Pseudomonas putida SQ1, participates in a sulfoquinovose degradation pathway. Also acts on succinate semialdehyde.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Felux, A.K., Spiteller, D., Klebensberger, J. and Schleheck, D. Entner-Doudoroff pathway for sulfoquinovose degradation in Pseudomonas putida SQ1. Proc. Natl. Acad. Sci. USA 112 (2015) E4298-E4305. [PMID: 26195800]