IUBMB Enzyme Nomenclature


Accepted name: aldehyde dehydrogenase (quinone)

Reaction: an aldehyde + a quinone + H2O = a carboxylate + a quinol

Other name(s): aldehyde dehydrogenase (acceptor)

Systematic name: aldehyde:quinone oxidoreductase

Comments: Wide specificity; acts on straight-chain aldehydes up to C10, aromatic aldehydes, glyoxylate and glyceraldehyde. The enzymes contains a PQQ cofactor and multiple hemes that deliver the electrons to the membrane quinone pool.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Ameyama, M. and Adachi, O. Aldehyde dehydrogenase from acetic acid bacteria, membrane-bound. Methods Enzymol. 89 (1982) 491-497.

2. Ameyama, M., Osada, K., Shinagawa, E., Matsushita, K. and Adachi, O. Purification and characterization of aldehyde dehydrogenase of Acetobacter aceti. Agric. Biol. Chem. 45 (1981) 1189-1890.

3. Patel, R.N., Hou, C.T., Derelanko, P. and Felix, A. Purification and properties of a heme-containing aldehyde dehydrogenase from Methylosinus trichosporium. Arch. Biochem. Biophys. 203 (1980) 654-662. [PMID: 6779711]

4. Gomez-Manzo, S., Chavez-Pacheco, J.L., Contreras-Zentella, M., Sosa-Torres, M.E., Arreguin-Espinosa, R., Perez de la Mora, M., Membrillo-Hernandez, J. and Escamilla, J.E. Molecular and catalytic properties of the aldehyde dehydrogenase of Gluconacetobacter diazotrophicus, a quinoheme protein containing pyrroloquinoline quinone, cytochrome b, and cytochrome c. J. Bacteriol. 192 (2010) 5718-5724. [PMID: 20802042]

[EC created 1983 as EC, modified 1989, transferred 2015 to EC ]

Return to EC 1.2.4 home page
Return to EC 1.2 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page