IUBMB Enzyme Nomenclature


Accepted name: 2-oxobutyrate synthase

Reaction: 2-oxobutanoate + CoA + 2 oxidized ferredoxin = propanoyl-CoA + CO2 + 2 reduced ferredoxin + H+

Other name(s): α-ketobutyrate-ferredoxin oxidoreductase; 2-ketobutyrate synthase; α-ketobutyrate synthase; 2-oxobutyrate-ferredoxin oxidoreductase

Systematic name: 2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propanoylating)

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, CAS registry number: 37251-04-0


1. Buchanan, B.B. Role of ferredoxin in the synthesis of α-ketobutyrate from propionyl coenzyme A and carbon dioxide by enzymes from photosynthetic and nonphotosynthetic bacteria. J. Biol. Chem. 244 (1969) 4218-4223. [PMID: 5800441]

[EC created 1972]

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