IUBMB Enzyme Nomenclature


Accepted name: 2,4-dichlorobenzoyl-CoA reductase

Reaction: 4-chlorobenzoyl-CoA + NADP+ + chloride = 2,4-dichlorobenzoyl-CoA + NADPH + H+

Systematic name: 4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating)

Comments: The enzyme, characterized from Corynebacterium strains able to grow on 2,4-dichlorobenzoate, forms part of the 2,4-dichlorobenzoate degradation pathway.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Romanov, V. and Hausinger, R.P. NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strain NTB-1 via 2,4-dichlorobenzoyl coenzyme A. J. Bacteriol. 178 (1996) 2656-2661. [PMID: 8626335]

[EC created 2000 as EC, modified 2011, transferred 2015 to EC]

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