Reaction: 2 sulochrin + O2 = 2 (–)-bisdechlorogeodin + 2 H2O
For diagram click here.
Other name(s): sulochrin oxidase
Systematic name: sulochrin:oxygen oxidoreductase (cyclizing, (–)-specific)
Comments: Also acts on several diphenols and phenylenediamines, but has low affinity for these substrates. Involved in the biosynthesis of mould metabolites related to the antibiotic griseofulvin.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 82469-87-2
References:
1. Nordlöv, H. and Gatenbeck, S. Enzymatic synthesis of (+)- and (–)-bisdechlorogeodin with sulochrin oxidase from Penicillium frequentans and Oospora sulphurea ochracea. Arch. Microbiol. 131 (1982) 208-211. [PMID: 7049104]