Reaction: β-cyclopiazonate + acceptor = α-cyclopiazonate + reduced acceptor
For diagram click here.
Other name(s): β-cyclopiazonate oxidocyclase; β-cyclopiazonic oxidocyclase; β-cyclopiazonate:(acceptor) oxidoreductase (cyclizing)
Systematic name: β-cyclopiazonate:acceptor oxidoreductase (cyclizing)
Comments: A flavoprotein (FAD). Cytochrome c and various dyes can act as acceptor. Cyclopiazonate is a microbial toxin.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9059-00-1
References:
1. Edmondson, D.E., Kenney, W.C. and Singer, T.P. Structural elucidation and properties of 8α-(N1-histidyl)riboflavin: the flavin component of thiamine dehydrogenase and β-cyclopiazonate oxidocyclase. Biochemistry 15 (1976) 2937-2945. [PMID: 8076]
2. Schabort, J.C. and Potgieter, D.J.J. β-Cyclopiazonate oxidocyclase from Penicillium cyclopium. II. Studies on electron acceptors, inhibitors, enzyme kinetics, amino acid composition, flavin prosthetic group and other properties. Biochim. Biophys. Acta 250 (1971) 329-345. [PMID: 5143340]