IUBMB Enzyme Nomenclature


Accepted name: 2-haloacrylate reductase

Reaction: (S)-2-chloropropanoate + NADP+ = 2-chloroacrylate + NADPH + H+

Other name(s): CAA43 (gene name)

Systematic name: (S)-2-chloropropanoate:NADP+ oxidoreductase

Comments: The enzyme acts in the degradation pathway of unsaturated organohalogen compounds by the bacterium Burkholderia sp. WS.

Links to other databases: BRENDA, EXPASY, KEGG Metacyc, PDB, CAS registry number:


1. Kurata, A., Kurihara, T., Kamachi, H. and Esaki, N. 2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds. J. Biol. Chem. 280 (2005) 20286-20291. [PMID: 15781461]

[EC created 2013]

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