IUBMB Enzyme Nomenclature


Accepted name: protochlorophyllide reductase

Reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+

For diagram of reaction click here.

Other name(s): NADPH2-protochlorophyllide oxidoreductase; NADPH—protochlorophyllide oxidoreductase; NADPH-protochlorophyllide reductase; protochlorophyllide oxidoreductase; protochlorophyllide photooxidoreductase; light-dependent protochlorophyllide reductase

Systematic name: chlorophyllide-a:NADP+ 7,8-oxidoreductase

Comments: The enzyme catalyses a light-dependent trans-reduction of the D-ring of protochlorophyllide; the product has the (7S,8S)-configuration.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 68518-04-7


1. Apel, K., Santel, H.-J., Redlinger, T.E. and Falk, H. The protochlorophyllide holochrome of barley (Hordeum vulgare L.). Isolation and characterization of the NADPH:protochlorophyllide oxidoreductase. Eur. J. Biochem. 111 (1980) 251-258. [PMID: 7439188]

2. Griffiths, W.T. Reconstitution of chlorophyllide formation by isolated etioplast membranes. Biochem. J. 174 (1978) 681-692. [PMID: 31865]

[EC created 1984]

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