IUBMB Enzyme Nomenclature


Accepted name: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase

Reaction: 2,6-dioxo-6-phenylhexanoate + NADP+ = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + NADPH + H+

Other name(s): 2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate) reductase

Systematic name: 2,6-dioxo-6-phenylhexanoate:NADP+ Δ2-oxidoreductase

Comments: Broad specificity; reduces a number of compounds produced by Pseudomonas from aromatic hydrocarbons by ring fission.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 104645-83-2


1. Omori, T., Ishigooka, H. and Minoda, Y. Purification and some properties of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid(HOPDA) reducing enzyme from Pseudomonas cruciviae S93B1 involved in the degradation of biphenyl. Agric. Biol. Chem. 50 (1986) 1513-1518.

[EC created 1989]

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