IUBMB Enzyme Nomenclature


Accepted name: cucurbitacin Δ23-reductase

Reaction: 23,24-dihydrocucurbitacin B + NAD(P)+ = cucurbitacin B + NAD(P)H + H+

Other name(s): NAD(P)H: cucurbitacin B Δ23-oxidoreductase

Systematic name: 23,24-dihydrocucurbitacin:NAD(P)+ Δ23-oxidoreductase

Comments: Requires Mn2+. Fe2+ or Zn2+ can replace Mn2+ to some extent.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37256-38-5


1. Schabort, J.C. and Potgieter, D.J.J. Cucurbitacin B Δ23-reductase from Cucurbita maxima. II. Cofactor requirements, enzyme kinetics, substrate specificity and other characteristics. Biochim. Biophys. Acta 151 (1968) 47-53. [PMID: 4384331]

2. Schabort, J.C., Potgieter, D.J.J. and de Villiers, V. Cucurbitacin B Δ23-reductase from Cucurbita maxima. I. Assay methods, isolation and purification. Biochim. Biophys. Acta 151 (1968) 33-46. [PMID: 5640163]

[EC created 1965]

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