IUBMB Enzyme Nomenclature


Accepted name: benzylmalonyl-CoA dehydrogenase

Reaction: benzylmalonyl-CoA + O2 = (E)-cinnamoyl-CoA + CO2 + H2O2

Other name(s): iaaF (gene name)

Systematic name: benzylmalonyl-CoA:oxygen oxidoreductase (decarboxylating)

Comments: The enzyme, characterized from the bacterium Aromatoleum aromaticum, is involved in degradation of (indol-3-yl)acetate, where it is believed to function on (2-aminobenzyl)malonyl-CoA.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Schuhle, K., Saft, M., Vogeli, B., Erb, T.J. and Heider, J. Benzylmalonyl-CoA dehydrogenase, an enzyme involved in bacterial auxin degradation. Arch. Microbiol. 203 (2021) 4149-4159. [PMID: 34059946]

[EC created 2022]

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