IUBMB Enzyme Nomenclature


Accepted name: coproporphyrinogen oxidase

Reaction: coproporphyrinogen III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

For diagram click here.

Other name(s): coproporphyrinogen III oxidase; coproporphyrinogenase

Systematic name: coproporphyrinogen:oxygen oxidoreductase (decarboxylating)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9076-84-0


1. Battle, A.M., Benson, A. and Rimington, C. Purification and properties of coproporphyrinogenase. Biochem. J. 97 (1965) 731-740. [PMID: 5881662]

2. Medlock, A.E. and Dailey, H.A. Human coproporphyrinogen oxidase is not a metalloprotein. J. Biol. Chem. 271 (1996) 32507-32510. [PMID: 8955072]

3. Kohno, H., Furukawa, T., Yoshinaga, T., Tokunaga, R. and Taketani, S. Coproporphyrinogen oxidase. Purification, molecular cloning, and induction of mRNA during erythroid differentiation. J. Biol. Chem. 268 (1993) 21359-21363. [PMID: 8407975]

[EC created 1972, modified 2003]

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