IUBMB Enzyme Nomenclature


Accepted name: acyl-CoA oxidase

Reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2

Other name(s): fatty acyl-CoA oxidase; acyl coenzyme A oxidase; fatty acyl-coenzyme A oxidase

Systematic name: acyl-CoA:oxygen 2-oxidoreductase

Comments: A flavoprotein (FAD). Acts on CoA derivatives of fatty acids with chain lengths from 8 to 18.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 61116-22-1


1. Kawaguchi, A., Tsubotani, S., Seyama, Y., Yamakawa, T., Osumi, T., Hashimoto, T., Kikuchi, T., Ando, M. and Okuda, S. Stereochemistry of dehydrogenation catalyzed by acyl-CoA oxidase. J. Biochem. (Tokyo) 88 (1980) 1481-1486. [PMID: 7462191]

2. Osumi, T., Hashimoto, T. and Ui, N. Purification and properties of acyl-CoA oxidase from rat liver. J. Biochem. (Tokyo) 87 (1980) 1735-1746. [PMID: 7400120]

[EC created 1986]

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