IUBMB Enzyme Nomenclature


Accepted name: 9,9'-dicis-ζ-carotene desaturase

Reaction: 9,9'-dicis-ζ-carotene + 2 quinone = 7,9,7',9'-tetracis-lycopene + 2 quinol (overall reaction)
(1a) 9,9'-dicis-ζ-carotene + a quinone = 7,9,9'-tricis-neurosporene + a quinol
(1b) 7,9,9'-tricis-neurosporene + a quinone = 7,9,7',9'-tetracis-lycopene + a quinol

For diagram of reaction click here.

Glossary: 7,9,7',9'-tetracis-lycopene = prolycopene

Other name(s): ζ-carotene desaturase; ZDS

Systematic name: 9,9'-dicis-ζ-corotene:quinone oxidoreductase

Comments: This enzyme is involved in carotenoid biosynthesis in plants and cyanobacteria.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Albrecht, M., Linden, H. and Sandmann, G. Biochemical characterization of purified ζ-carotene desaturase from Anabaena PCC 7120 after expression in E. coli. Eur. J. Biochem. 236 (1996) 115-120. [PMID: 8617254]

2. Josse, E.M., Simkin, A.J., Gaffe, J., Laboure, A.M., Kuntz, M. and Carol, P. A plastid terminal oxidase associated with carotenoid desaturation during chromoplast differentiation. Plant Physiol. 123 (2000) 1427-1436. [PMID: 10938359]

3. Breitenbach, J., Kuntz, M., Takaichi, S. and Sandmann, G. Catalytic properties of an expressed and purified higher plant type ζ-carotene desaturase from Capsicum annuum. Eur. J. Biochem. 265 (1999) 376-383. [PMID: 10491195]

4. Breitenbach, J. and Sandmann, G. ζ-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene. Planta 220 (2005) 785-793. [PMID: 15503129]

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