Reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH + H+
Systematic name: L-lysine:NAD+ oxidoreductase (deaminating, cyclizing)
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 68073-29-0
References:
1. Burgi, W., Richterich, R. and Colombo, J.P. L-Lysine dehydrogenase deficiency in a patient with congenital lysine intolerance. Nature (Lond.) 211 (1966) 854-855. [PMID: 4291003]