Reaction: L-tryptophan + NAD(P)+ + H2O = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+
Other name(s): NAD(P)+-L-tryptophan dehydrogenase; L-tryptophan dehydrogenase; L-Trp-dehydrogenase; TDH
Systematic name: L-tryptophan:NAD(P)+ oxidoreductase (deaminating)
Comments: Activated by Ca2+.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 94047-13-9
References:
1. Vackova, K., Mehta, A. and Kutacek, M. Tryptophan aminotransferase and tryptophan dehydrogenase - activities in some cell compartments of spinach leaves - the effect of calcium-ions on tryptophan dehydrogenase. Biol. Plant. 27 (1985) 154-158.