Reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+
Other name(s): glutamic dehydrogenase; glutamate dehydrogenase [NAD(P)]
Systematic name: L-glutamate:NAD(P)+ oxidoreductase (deaminating)
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9029-12-3
References:
1. Olson, J.A. and Anfinsen, C.B. The crystallization and characterization of L-glutamic acid dehydrogenase. J. Biol. Chem. 197 (1952) 67-79.
2. Smith, E.L., Austen, B.M., Blumenthal, K.M. and Nyc, J.F. Glutamate dehydrogenases. In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 11, Academic Press, New York, 1975, p. 293-367.
3. Strecker, H.J. Glutamic dehydrogenase. Arch. Biochem. Biophys. 46 (1953) 128-140.