Reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+
Other name(s): glutamic dehydrogenase; dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)); glutamic acid dehydrogenase; L-glutamate dehydrogenase; L-glutamic acid dehydrogenase; NAD(P)-glutamate dehydrogenase; NAD(P)H-dependent glutamate dehydrogenase; glutamate dehydrogenase (NADP)
Systematic name: L-glutamate:NADP+ oxidoreductase (deaminating)
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9029-11-2
References:
1. Coulton, J.W. and Kapoor, M. Purification and some properties of the glutamate dehydrogenase of Salmonella typhimurium. Can. J. Microbiol. 19 (1973) 427-438. [PMID: 4144743]
2. Grisolia, S., Quijada, C.L. and Fernandez, M. Glutamate dehydrogenase from yeast and from animal tissues. Biochim. Biophys. Acta 81 (1964) 61-70.
3. Shiio, I. and Ozaki, H. Regulation of nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase from Brevibacterium flavum, a glutamate-producing bacterium. J. Biochem. (Tokyo) 68 (1970) 633-647. [PMID: 4394939]
4. Smith, E.L., Austen, B.M., Blumenthal, K.M. and Nyc, J.F. Glutamate dehydrogenases. In: Boyer, P.D. (Ed.) T he Enzymes, 3rd ed., vol. 11, Academic Press, New York, 1975, p. 293-367.