Reaction: an L-amino acid + H2O + NAD+ = a 2-oxo carboxylate + NH3 + NADH + H+
Systematic name: L-amino-acid:NAD+ oxidoreductase (deaminating)
Comments: Acts on aliphatic amino acids.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9029-13-4
References:
1. Nisman, B. and Mager, J. Diphosphopyridine nucleotide and phosphate requirement for oxidation of amino-acids by cell-free extracts of obligate anaerobes. Nature (Lond.) 169 (1952) 243-244.