Reaction: L-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + H2O2
Other name(s): L-lysine α-oxidase; L-lysyl-α-oxidase
Systematic name: L-lysine:oxygen 2-oxidoreductase (deaminating)
Comments: Also acts, more slowly, on L-ornithine, L-phenylalanine, L-arginine and L-histidine.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 70132-14-8
1. Kusakabe, H., Kodama, K., Kuninaka, A., Yoshino, H., Misono, H. and Soda, K. A new antitumor enzyme, L-lysine α-oxidase from Trichoderma viride. Purification and enzymological properties. J. Biol. Chem. 255 (1980) 976-981. [PMID: 6101334]