IUBMB Enzyme Nomenclature

EC 1.5.1.24

Accepted name: N5-(carboxyethyl)ornithine synthase

Reaction: N5-(L-1-carboxyethyl)-L-ornithine + NADP+ + H2O = L-ornithine + pyruvate + NADPH + H+

Systematic name: N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)

Comments: In the reverse direction, L-lysine can act instead of L-ornithine, but more slowly. Acts on the amino group. cf. EC 1.5.1.16 D-lysopine dehydrogenase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 129070-70-8

References:

1. Thompson, J. N5-(L-1-Carboxyethyl)-L-ornithine:NADP+ oxidoreductase from Streptococcus lactis. Purification and partial characterization. J. Biol. Chem. 264 (1989) 9592-9601. [PMID: 2498334]

[EC 1.5.1.24 created 1990]


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