IUBMB Enzyme Nomenclature


Accepted name: thiomorpholine-carboxylate dehydrogenase

Reaction: thiomorpholine 3-carboxylate + NAD(P)+ = 3,4-dehydro-thiomorpholine-3-carboxylate + NAD(P)H + H+

For diagram of reaction click here.

Other name(s): ketimine reductase; ketimine-reducing enzyme

Systematic name: thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase

Comments: The product is the cyclic imine of the 2-oxoacid corresponding to S-(2-aminoethyl)cysteine. In the reverse direction, a number of other cyclic unsaturated compounds can act as substrates, but more slowly.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 115232-54-7


1. Nardini, M., Ricci, G., Caccuri, A.M., Solinas, S.P., Vesci, L. and Cavallini, D. Purification and characterization of a ketimine-reducing enzyme. Eur. J. Biochem. 173 (1988) 689-694. [PMID: 3371353]

[EC created 1990]

Return to EC 1.5.1 home page
Return to EC 1.5 home page
Return to EC 1 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page