IUBMB Enzyme Nomenclature


Accepted name: sarcosine oxidase

Reaction: sarcosine + H2O + O2 = glycine + formaldehyde + H2O2

Systematic name: sarcosine:oxygen oxidoreductase (demethylating)

Comments: A flavoprotein (FAD). The flavin is both covalently and non-covalently bound in a molar ratio of 1:1.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, PDB, CAS registry number: 9029-22-5


1. Hayashi, S., Nakamura, S. and Suzuki, M. Corynebacterium sarcosine oxidase: a unique enzyme having covalently-bound and noncovalently-bound flavins. Biochem. Biophys. Res. Commun. 96 (1980) 924-930. [PMID: 6158947]

2. Mori, N., Sano, M., Tani, Y. and Yamada, H. Purification and propertie of sarcosine oxidase from Cylindrocarpon didymum M-1. Agric. Biol. Chem. 44 (1980) 1391-1397.

3. Suzuki, M. Purification and some properties of sarcosine oxidase from Corynebacterium sp. U-96. J. Biochem. (Tokyo) 89 (1981) 599-607. [PMID: 7240129]

[EC created 1961]

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