IUBMB Enzyme Nomenclature


Accepted name: coenzyme F420 oxidoreductase (ferredoxin)

Reaction: reduced coenzyme F420 + 2 oxidized ferredoxin = oxidized coenzyme F420 + 2 reduced ferredoxin + 2 H+

For diagram of reaction, click here

Glossary: oxidized coenzyme F420 = N-(N-{O-[5-(8-hydroxy-2,4-dioxo-2,3,4,10-tetrahydropyrimido[4,5-b]quinolin-10-yl)-5-deoxy-L-ribityl-1-phospho]-(S)-lactyl}-γ-L-glutamyl)-L-glutamate

Other name(s): Fd:F420 oxidoreductase; FpoF protein; ferredoxin:F420 oxidoreductase

Systematic name: coenzyme F420:ferredoxin oxidoreductase

Comments: The enzyme from the archaeon Methanosarcina mazei contains iron-sulfur centres and FAD.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Welte, C. and Deppenmeier, U. Re-evaluation of the function of the F420 dehydrogenase in electron transport of Methanosarcina mazei. FEBS J. 278 (2011) 1277-1287. [PMID: 21306561]

[EC created 2013]

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