IUBMB Enzyme Nomenclature


Accepted name: D-proline dehydrogenase

Reaction: D-proline + oxidized acceptor = 1-pyrroline-2-carboxylate + reduced acceptor

Other name(s): D-Pro DH; D-Pro dehydrogenase; dye-linked D-proline dehydrogenase

Systematic name: D-proline:acceptor oxidoreductase

Comments: A flavoprotein (FAD). The enzyme prefers D-proline and acts on other D-amino acids with lower efficiency.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Tani, Y., Tanaka, K., Yabutani, T., Mishima, Y., Sakuraba, H., Ohshima, T. and Motonaka, J. Development of a D-amino acids electrochemical sensor based on immobilization of thermostable D-proline dehydrogenase within agar gel membrane. Anal Chim Acta 619 (2008) 215-220. [PMID: 18558115]

2. Satomura, T., Kawakami, R., Sakuraba, H. and Ohshima, T. Dye-linked D-proline dehydrogenase from hyperthermophilic archaeon Pyrobaculum islandicum is a novel FAD-dependent amino acid dehydrogenase. J. Biol. Chem. 277 (2002) 12861-12867. [PMID: 11823469]

[EC created 2010]

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