IUBMB Enzyme Nomenclature


Accepted name: nitrate reductase (NADH)

Reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+

Other name(s): assimilatory nitrate reductase (ambiguous); NADH-nitrate reductase; NADH-dependent nitrate reductase; assimilatory NADH: nitrate reductase; nitrate reductase (NADH2); NADH2:nitrate oxidoreductase

Systematic name: nitrite:NAD+ oxidoreductase

Comments: An iron-sulfur molybdenum flavoprotein.

Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9013-03-0


1. Fewson, C.A. and Nicholas, D.J.D. Nitrate reductase from Pseudomonas aeruginosa. Biochim. Biophys. Acta 49 (1961) 335-349.

2. Nason, A. Nitrate reductases. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, pp. 587-607.

3. Nicholas, D.J.D. and Nason, A. Diphosphopyridine nucleotide-nitrate reductase from Escherichia coli. J. Bacteriol. 69 (1955) 580-583.

4. Spencer, D. A reduced diphosphopyridine-specific nitrate reductase from germinating wheat. Aust. J. Biol. Sci. 12 (1959) 181-189.

5. Berks, B.C., Ferguson, S.J., Moir, J.W. and Richardson, D.J. Enzymes and associated electron transport systems that catalyse the respiratory reduction of nitrogen oxides and oxyanions. Biochim. Biophys. Acta 1232 (1995) 97-173. [PMID: 8534676]

[EC created 1961 as EC, transferred 2002 to EC]

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