Reaction: 3-sulfanyl-2-(sulfanylmethyl)propanoate + NAD+ = asparagusate + NADH + H+
For diagram click here.
Glossary: 3-sulfanyl-2-(sulfanylmethyl)propanoate = 3-mercapto-2-mercaptomethylpropanoate (deprecated)
asparagusate = 1,2-dithiolane-4-carboxylate
Other name(s): asparagusate dehydrogenase; asparagusic dehydrogenase; asparagusate reductase (NADH2); NADH2:asparagusate oxidoreductase; 3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase
Systematic name: 3-sulfanyl-2-(sulfanylmethyl)propanoate:NAD+ oxidoreductase
Comments: Also acts on lipoate.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 56126-52-4
References:
1. Yanagawa, H. and Egami, F. Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria. Biochim. Biophys. Acta 384 (1975) 342-352. [PMID: 1125255]
2. Yanagawa, H. and Egami, F. Asparagusate dehydrogenases and lipoyl dehydrogenase from asparagus mitochondria. Physical, chemical, and enzymatic properties. J. Biol. Chem. 251 (1976) 3637-3644. [PMID: 180003]