IUBMB Enzyme Nomenclature


Accepted name: dimethyl sulfide:cytochrome c2 reductase

Reaction: dimethyl sulfide + 2 ferricytochrome c2 + H2O = dimethyl sulfoxide + 2 ferrocytochrome c2 + 2 H+

For diagram of reaction click here.

Other name(s): Ddh (gene name)

Systematic name: dimethyl sulfide:ferricytochrome-c2 oxidoreductase

Comments: The enzyme from Rhodovulum sulfidophilum binds molybdopterin guanine dinucleotide, heme b and [4Fe-4S] clusters.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Hanlon, S.P., Toh, T.H., Solomon, P.S., Holt, R.A. and McEwan, A.G. Dimethylsulfide:acceptor oxidoreductase from Rhodobacter sulfidophilus. The purified enzyme contains b-type haem and a pterin molybdenum cofactor. Eur. J. Biochem. 239 (1996) 391-396. [PMID: 8706745]

2. McDevitt, C.A., Hugenholtz, P., Hanson, G.R. and McEwan, A.G. Molecular analysis of dimethyl sulphide dehydrogenase from Rhodovulum sulfidophilum: its place in the dimethyl sulphoxide reductase family of microbial molybdopterin-containing enzymes. Mol. Microbiol. 44 (2002) 1575-1587. [PMID: 12067345]

[EC created 2011]

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