Reaction: 2 glutathione + O2 = glutathione disulfide + H2O2
Systematic name: glutathione:oxygen oxidoreductase
Comments: A flavoprotein (FAD). Also acts, more slowly, on L-cysteine and several other thiols.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 55467-56-6
References:
1. Kusakabe, H., Kuninaka, A. and Yoshino, H. Purification and properties of a new enzyme, glutathione oxidase from Penicillium sp.K-6-5. Agric. Biol. Chem. 46 (1982) 2057-2067.