IUBMB Enzyme Nomenclature


Accepted name: glutathione-cystine transhydrogenase

Reaction: 2 glutathione + cystine = glutathione disulfide + 2 cysteine

Other name(s): GSH-cystine transhydrogenase; NADPH-dependent GSH-cystine transhydrogenase

Systematic name: glutathione:cystine oxidoreductase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37256-49-8


1. Nagai, S. and Black, S. A thiol-disulfide transhydrogenase from yeast. J. Biol. Chem. 243 (1968) 1942-1947. [PMID: 5646485]

[EC created 1972]

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