Reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene
Other name(s): 1,2,3,5-tetrahydroxybenzene hydroxyltransferase; 1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase; 1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase); pyrogallol hydroxyltransferase; 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase
Systematic name: 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase
Comments: 1,2,3,5-Tetrahydroxybenzene acts as a co-substrate for the conversion of pyrogallol into phloroglucinol, and for a number of similar isomerizations. The enzyme is provisionally listed here, but might be considered as the basis for a new class in the transferases, analogous to the aminotransferases.
Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 176591-26-7
References:
1. Brune, A. and Schink, B. Pyrogallol-to-phloroglucinol conversion and other hydroxyl-transfer reactions catalyzed by cell extracts of Pelobacter acidigallici. J. Bacteriol. 172 (1990) 1070-1076. [PMID: 2298693]