Nomenclature Committee of the
International Union of Biochemistry and Molecular Biology (NC-IUBMB)

Enzyme Nomenclature

Contents

Continued from contents EC 1.1 to EC 1.3

EC 1.4 Acting on the CH-NH2 group of donors

EC 1.4.1 With NAD+ or NADP+ as acceptor

EC 1.4.1.1 alanine dehydrogenase
EC 1.4.1.2 glutamate dehydrogenase
EC 1.4.1.3 glutamate dehydrogenase [NAD(P)+]
EC 1.4.1.4 glutamate dehydrogenase (NADP+)
EC 1.4.1.5 L-amino-acid dehydrogenase
EC 1.4.1.6 deleted, included in EC 1.4.4.1
EC 1.4.1.7 serine 2-dehydrogenase
EC 1.4.1.8 valine dehydrogenase (NADP+)
EC 1.4.1.9 leucine dehydrogenase
EC 1.4.1.10 glycine dehydrogenase
EC 1.4.1.11 L-erythro-3,5-diaminohexanoate dehydrogenase
EC 1.4.1.12 2,4-diaminopentanoate dehydrogenase
EC 1.4.1.13 glutamate synthase (NADPH)
EC 1.4.1.14 glutamate synthase (NADH)
EC 1.4.1.15 lysine dehydrogenase
EC 1.4.1.16 diaminopimelate dehydrogenase
EC 1.4.1.17 N-methylalanine dehydrogenase
EC 1.4.1.18 lysine 6-dehydrogenase
EC 1.4.1.19 tryptophan dehydrogenase
EC 1.4.1.20 phenylalanine dehydrogenase
EC 1.4.1.21 aspartate dehydrogenase
EC 1.4.1.22 deleted
EC 1.4.1.23 valine dehydrogenase (NAD+)
EC 1.4.1.24 3-dehydroquinate synthase II
EC 1.4.1.25 L-arginine dehydrogenase
EC 1.4.1.26 2,4-diaminopentanoate dehydrogenase (NAD+)
EC 1.4.1.27 glycine cleavage system
EC 1.4.1.28 secondary-alkyl amine dehydrogenase [NAD(P)+]
EC 1.4.2 With a cytochrome as acceptor
EC 1.4.2.1 glycine dehydrogenase (cytochrome)
EC 1.4.2.2 nicotine dehydrogenase
EC 1.4.2.3 pseudooxynicotine dehydrogenase
EC 1.4.3 With oxygen as acceptor
EC 1.4.3.1 D-aspartate oxidase
EC 1.4.3.2 L-amino-acid oxidase
EC 1.4.3.3 D-amino-acid oxidase
EC 1.4.3.4 amine oxidase
EC 1.4.3.5 pyridoxal 5'-phosphate synthase
EC 1.4.3.6 deleted now EC 1.4.3.21 and EC 1.4.3.22
EC 1.4.3.7 D-glutamate oxidase
EC 1.4.3.8 ethanolamine oxidase
EC 1.4.3.9 deleted, included in EC 1.4.3.4
EC 1.4.3.10 putrescine oxidase
EC 1.4.3.11 L-glutamate oxidase
EC 1.4.3.12 cyclohexylamine oxidase
EC 1.4.3.13 protein-lysine 6-oxidase
EC 1.4.3.14 L-lysine oxidase
EC 1.4.3.15 D-glutamate(D-aspartate) oxidase
EC 1.4.3.16 L-aspartate oxidase
EC 1.4.3.17 now EC 1.3.3.10
EC 1.4.3.18 deleted, not approved
EC 1.4.3.19 glycine oxidase
EC 1.4.3.20 L-lysine 6-oxidase
EC 1.4.3.21 primary-amine oxidase
EC 1.4.3.22 diamine oxidase
EC 1.4.3.23 7-chloro-L-tryptophan oxidase
EC 1.4.3.24 transferred now EC 1.4.2.3
EC 1.4.3.25 L-arginine oxidase
EC 1.4.3.26 pre-mycofactocin synthase
EC 1.4.3.27 homospermidine oxidase
EC 1.4.4 With a disulfide as acceptor
EC 1.4.4.1 now EC 1.21.4.1
*EC 1.4.4.2 glycine dehydrogenase (aminomethyl-transferring)
EC 1.4.5 With a quinone or similar compound as acceptor
EC 1.4.5.1 D-amino acid dehydrogenase (quinone)
EC 1.4.7 With an iron-sulfur protein as acceptor
EC 1.4.7.1 glutamate synthase (ferredoxin)

EC 1.4.9 With a copper protein as acceptor

EC 1.4.9.1 methylamine dehydrogenase (amicyanin)
EC 1.4.9.2 aralkylamine dehydrogenase (azurin)
EC 1.4.98 With other, known, physiological acceptors
EC 1.4.98.1 transferred now EC 1.4.9.1
EC 1.4.99 With unknown physiological acceptors
EC 1.4.99.1 transferred now EC 1.4.99.6
EC 1.4.99.2 taurine dehydrogenase
EC 1.4.99.3 transferred now EC 1.4.98.1
EC 1.4.99.4 transferred now EC 1.4.9.2
EC 1.4.99.5 glycine dehydrogenase (cyanide-forming) EC 1.4.99.6 D-arginine dehydrogenase
EC 1.5 Acting on the CH-NH group of donors

EC 1.5.1 With NAD+ or NADP+ as acceptor

EC 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]
EC 1.5.1.2 pyrroline-5-carboxylate reductase
EC 1.5.1.3 dihydrofolate reductase
EC 1.5.1.4 deleted, included in EC 1.5.1.3
EC 1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
EC 1.5.1.6 formyltetrahydrofolate dehydrogenase
EC 1.5.1.7 saccharopine dehydrogenase (NAD+, L-lysine-forming)
EC 1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming)
EC 1.5.1.9 saccharopine dehydrogenase (NAD+, L-glutamate-forming)
EC 1.5.1.10 saccharopine dehydrogenase (NADP+, L-glutamate-forming)
EC 1.5.1.11 D-octopine dehydrogenase
EC 1.5.1.12 transferred now EC 1.2.1.88
EC 1.5.1.13 now EC 1.17.1.5
EC 1.5.1.14 deleted, included in EC 1.5.1.21
EC 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
EC 1.5.1.16 D-lysopine dehydrogenase
EC 1.5.1.17 alanopine dehydrogenase
EC 1.5.1.18 ephedrine dehydrogenase
EC 1.5.1.19 D-nopaline dehydrogenase
EC 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
EC 1.5.1.22 strombine dehydrogenase
EC 1.5.1.23 tauropine dehydrogenase
EC 1.5.1.24 N5-(carboxyethyl)ornithine synthase
EC 1.5.1.25 thiomorpholine-carboxylate dehydrogenase
EC 1.5.1.26 β-alanopine dehydrogenase
EC 1.5.1.27 1,2-dehydroreticulinium reductase (NADPH)
EC 1.5.1.28 opine dehydrogenase
EC 1.5.1.29 deleted, now covered by EC 1.5.1.38, EC 1.5.1.39 and EC 1.5.1.41
EC 1.5.1.30 flavin reductase (NADPH)
EC 1.5.1.31 berberine reductase
EC 1.5.1.32 vomilenine reductase
EC 1.5.1.33 pteridine reductase
EC 1.5.1.34 6,7-dihydropteridine reductase
EC 1.5.1.35 deleted, same as EC 1.2.1.19
EC 1.5.1.36 flavin reductase (NADH)
EC 1.5.1.37 FAD reductase (NADH)
EC 1.5.1.38 FMN reductase (NADPH)
EC 1.5.1.39 FMN reductase [NAD(P)H]
EC 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
EC 1.5.1.41 riboflavin reductase [NAD(P)H]
EC 1.5.1.42 FMN reductase (NADH)
EC 1.5.1.43 carboxynorspermidine synthase
EC 1.5.1.44 festuclavine dehydrogenase
EC 1.5.1.45 FAD reductase [NAD(P)H]
EC 1.5.1.46 agroclavine dehydrogenase
EC 1.5.1.47 dihydromethanopterin reductase [NAD(P)+]
EC 1.5.1.48 2-methyl-1-pyrroline reductase
EC 1.5.1.49 1-pyrroline-2-carboxylate reductase [NAD(P)H]
EC 1.5.1.50 dihydromonapterin reductase
EC 1.5.1.51 N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase
EC 1.5.1.52 staphylopine dehydrogenase
EC 1.5.1.53 methylenetetrahydrofolate reductase (NADPH)
EC 1.5.1.54 methylenetetrahydrofolate reductase (NADH)
EC 1.5.1.55 carboxyaminopropylagmatine dehydrogenase
EC 1.5.1.56 3,17-didehydrostemmadenine reductase
EC 1.5.1.57 18-hydroxynorfluorocurarine reductase
EC 1.5.3 With oxygen as acceptor
EC 1.5.3.1sarcosine oxidase (formaldehyde-forming)
EC 1.5.3.2 N-methyl-L-amino-acid oxidase
EC 1.5.3.3 deleted
EC 1.5.3.4 N6-methyl-lysine oxidase
EC 1.5.3.5 (S)-6-hydroxynicotine oxidase
EC 1.5.3.6 (R)-6-hydroxynicotine oxidase
EC 1.5.3.7 L-pipecolate oxidase
EC 1.5.3.8 deleted, included in EC 1.3.3.8
EC 1.5.3.9 now EC 1.21.3.3
EC 1.5.3.10 dimethylglycine oxidase
EC 1.5.3.11 deleted, now EC 1.5.3.13, EC 1.5.3.14, EC 1.5.3.15, EC 1.5.3.16 and EC 1.5.3.17
EC 1.5.3.12 dihydrobenzophenanthridine oxidase
EC 1.5.3.13 N1-acetylpolyamine oxidase
EC 1.5.3.14 polyamine oxidase (propane-1,3-diamine-forming)
EC 1.5.3.15 N8-acetylspermidine oxidase (propane-1,3-diamine-forming)
EC 1.5.3.16 spermine oxidase
EC 1.5.3.17 non-specific polyamine oxidase
EC 1.5.3.18 L-saccharopine oxidase
EC 1.5.3.19 4-methylaminobutanoate oxidase (formaldehyde-forming)
EC 1.5.3.20 N-alkylglycine oxidase
EC 1.5.3.21 4-methylaminobutanoate oxidase (methylamine-forming)
EC 1.5.3.22 coenzyme F420H2 oxidase
EC 1.5.3.23 glyphosate oxidoreductase
EC 1.5.3.24 sarcosine oxidase (5,10-methylenetetrahydrofolate-forming)
EC 1.5.3.25 fructosyl amine oxidase (glucosone-forming)
EC 1.5.3.26 fructosyl amine oxidase (fructosamine-forming)
EC 1.5.3.27 2-(methylaminoethyl)phosphonate oxidase
EC 1.5.4 With a disulfide as acceptor
EC 1.5.4.1 pyrimidodiazepine synthase
EC 1.5.5 With a quinone or similar compound as acceptor
EC 1.5.5.1 electron-transferring-flavoprotein dehydrogenase
EC 1.5.5.2 proline dehydrogenase
EC 1.5.5.3 hydroxyproline dehydrogenase
EC 1.5.7 With an iron-sulfur protein as acceptor
EC 1.5.7.1 methylenetetrahydrofolate reductase (ferredoxin)
EC 1.5.7.2 coenzyme F420 oxidoreductase (ferredoxin)
EC 1.5.7.3 N,N-dimethylglycine/sarcosine dehydrogenase (ferredoxin)
EC 1.5.8 With a flavin as acceptor
EC 1.5.8.1 dimethylamine dehydrogenase
EC 1.5.8.2 trimethylamine dehydrogenase
EC 1.5.8.3 sarcosine dehydrogenase
EC 1.5.8.4 dimethylglycine dehydrogenase
EC 1.5.98 With another, known, physiological acceptor
EC 1.5.98.1 methylenetetrahydromethanopterin dehydrogenase
EC 1.5.98.2 5,10-methylenetetrahydromethanopterin reductase
EC 1.5.98.3 coenzyme F420:methanophenazine dehydrogenase
EC 1.5.99 With unknown physiological acceptors
EC 1.5.99.1 transferred now EC 1.5.8.3
EC 1.5.99.2 transferred now EC 1.5.8.4
EC 1.5.99.3 L-pipecolate dehydrogenase
EC 1.5.99.4 nicotine 6-hydroxylase
EC 1.5.99.5 methylglutamate dehydrogenase
EC 1.5.99.6 spermidine dehydrogenase
EC 1.5.99.7 now EC 1.5.8.2
EC 1.5.99.8 proline dehydrogenase
EC 1.5.99.8 transferred now EC 1.5.5.2
EC 1.5.99.9 transferred now EC 1.5.98.1
EC 1.5.99.10 now EC 1.5.8.1
EC 1.5.99.11 transferred now EC 1.5.98.2
EC 1.5.99.12 cytokinin dehydrogenase
EC 1.5.99.13 D-proline dehydrogenase
EC 1.5.99.14 6-hydroxypseudooxynicotine dehydrogenase
EC 1.5.99.15 dihydromethanopterin reductase (acceptor)
EC 1.5.99.16 2-(methylaminoethyl)phosphonate dehydrogenase (acceptor)
EC 1.6 Acting on NADH or NADPH

EC 1.6.1 With NAD+ or NADP+ as acceptor

EC 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
EC 1.6.1.2 transferred now EC 7.1.1.1
EC 1.6.1.3 NAD(P)+ transhydrogenase
EC 1.6.1.4 NAD(P)+ transhydrogenase (ferredoxin)
EC 1.6.1.5 transferred, now EC 7.1.1.1
EC 1.6.2 With a heme protein as acceptor
EC 1.6.2.1 now EC 1.6.99.3
EC 1.6.2.2 cytochrome-b5 reductase
EC 1.6.2.3 deleted
EC 1.6.2.4 NADPH—hemoprotein reductase
EC 1.6.2.5 NADPH—cytochrome-c2 reductase
EC 1.6.2.6 leghemoglobin reductase
EC 1.6.3 With oxygen as acceptor
EC 1.6.3.1 NAD(P)H oxidase (H2O2-forming)
EC 1.6.3.2 NAD(P)H oxidase (H2O-forming)
EC 1.6.3.3 NADH oxidase (H2O2-forming)
EC 1.6.3.4 NADH oxidase (H2O-forming)
EC 1.6.3.5 renalase
EC 1.6.4 With a disulfide as acceptor
EC 1.6.4.1 now EC 1.8.1.6
EC 1.6.4.2 now EC 1.8.1.7
EC 1.6.4.3 now EC 1.8.1.4
EC 1.6.4.4 now EC 1.8.1.8
EC 1.6.4.5 now EC 1.8.1.9
EC 1.6.4.6 now EC 1.8.1.10
EC 1.6.4.7 now EC 1.8.1.11
EC 1.6.4.8 now EC 1.8.1.12
EC 1.6.4.9 now EC 1.8.1.13
EC 1.6.4.10 now EC 1.8.1.14
EC 1.6.5 With a quinone or similar compound as acceptor
EC 1.6.5.1 deleted
EC 1.6.5.2 NAD(P)H dehydrogenase (quinone)
EC 1.6.5.3 transferred, now EC 7.1.1.2
EC 1.6.5.4 monodehydroascorbate reductase (NADH)
EC 1.6.5.5 NADPH:quinone reductase
EC 1.6.5.6 p-benzoquinone reductase (NADPH)
EC 1.6.5.7 2-hydroxy-1,4-benzoquinone reductase
EC 1.6.5.8 transferred, now EC 7.2.1.1
EC 1.6.5.9 NADH:ubiquinone reductase (non-electrogenic)
EC 1.6.5.10 NADPH dehydrogenase (quinone)
EC 1.6.5.11 deleted, identical to EC 1.6.5.9
EC 1.6.5.12 demethylphylloquinone reductase
EC 1.6.6 With a nitrogenous group as acceptor
EC 1.6.6.1 now EC 1.7.1.1
EC 1.6.6.2 now EC 1.7.1.2
EC 1.6.6.3 now EC 1.7.1.3
EC 1.6.6.4 now EC 1.7.1.4
EC 1.6.6.5 now EC 1.7.99.3
EC 1.6.6.6 now EC 1.7.1.5
EC 1.6.6.7 now EC 1.7.1.6
EC 1.6.6.8 now EC 1.7.1.7
EC 1.6.6.9 deleted
EC 1.6.6.10 now EC 1.7.1.9
EC 1.6.6.11 now EC 1.7.1.10
EC 1.6.6.12 now EC 1.7.1.11
EC 1.6.6.13 now EC 1.7.1.12
EC 1.6.7 With a iron-sulfur protein as acceptor
EC 1.6.7.1 now EC 1.18.1.2
EC 1.6.7.2 now EC 1.18.1.1
EC 1.6.8 With a flavin as acceptor
EC 1.6.8.1 now EC 1.5.1.29
EC 1.6.8.2 now EC 1.5.1.30
EC 1.6.99 With unknown physiological acceptors
EC 1.6.99.1 NADPH dehydrogenase
EC 1.6.99.2 now EC 1.6.5.2
EC 1.6.99.3 covered by EC 7.1.1.2
EC 1.6.99.4 now EC 1.18.1.2
EC 1.6.99.5 transferred now EC 1.6.5.11
EC 1.6.99.6 NADPH dehydrogenase (quinone)
EC 1.6.99.6 transferred now EC 1.6.5.10
EC 1.6.99.7 now EC 1.5.1.34
EC 1.6.99.8 now EC 1.16.1.3
EC 1.6.99.9 now EC 1.16.1.4
EC 1.6.99.10 now included with EC 1.5.1.34
EC 1.6.99.11 now EC 1.16.1.5
EC 1.6.99.12 now EC 1.16.1.6
EC 1.6.99.13 now EC 1.16.1.7
EC 1.7 Acting on other nitrogenous compounds as donors

EC 1.7.1 With NAD+ or NADP+ as acceptor

EC 1.7.1.1 nitrate reductase (NADH)
EC 1.7.1.2 nitrate reductase [NAD(P)H]
EC 1.7.1.3 nitrate reductase (NADPH)
EC 1.7.1.4 nitrite reductase [NAD(P)H]
EC 1.7.1.5 hyponitrite reductase
EC 1.7.1.6 azobenzene reductase
EC 1.7.1.7 GMP reductase
EC 1.7.1.8 Deleted entry: withdrawn in the light of further information on the acceptor
EC 1.7.1.9 nitroquinoline-N-oxide reductase
EC 1.7.1.10 hydroxylamine reductase (NADH)
EC 1.7.1.11 4-(dimethylamino)phenylazoxybenzene reductase
EC 1.7.1.12 N-hydroxy-2-acetamidofluorene reductase
EC 1.7.1.13 preQ1 reductase
EC 1.7.1.14 nitric oxide reductase [NAD(P), nitrous oxide-forming]
EC 1.7.1.15 nitrite reductase (NADH)
EC 1.7.1.16 nitrobenzene nitroreductase
EC 1.7.1.17 FMN-dependent NADH-azoreductase
EC 1.7.2 With a cytochrome as acceptor
EC 1.7.2.1 nitrite reductase (NO-forming)
EC 1.7.2.2 nitrite reductase (cytochrome; ammonia-forming)
EC 1.7.2.3 trimethylamine-N-oxide reductase
EC 1.7.2.4 nitrous-oxide reductase
EC 1.7.2.5 nitric oxide reductase (cytochrome c)
EC 1.7.2.6 hydroxylamine dehydrogenase
EC 1.7.2.7 hydrazine synthase
EC 1.7.2.8 hydrazine dehydrogenase
EC 1.7.2.9 hydroxylamine oxidase
EC 1.7.3 With oxygen as acceptor
EC 1.7.3.1 nitroalkane oxidase
EC 1.7.3.2 acetylindoxyl oxidase
EC 1.7.3.3 factor-independent urate hydroxylase
EC 1.7.3.4 deleted now covered by EC 1.7.2.6 and EC 1.7.3.6
EC 1.7.3.5 3-aci-nitropropanoate oxidase
EC 1.7.3.6 hydroxylamine oxidase (cytochrome)
EC 1.7.5 With a quinone or similar compound as acceptor
EC 1.7.5.1 nitrate reductase
EC 1.7.5.2 nitric oxide reductase (menaquinol)
EC 1.7.6 With a nitrogenous group as acceptor
EC 1.7.6.1 nitrite dismutase
EC 1.7.7 With an iron-sulfur protein as acceptor
EC 1.7.7.1 ferredoxin—nitrite reductase
EC 1.7.7.2 ferredoxin—nitrate reductase
EC 1.7.99 With unknown physiological acceptors
EC 1.7.99.1 hydroxylamine reductase
EC 1.7.99.2 deleted
EC 1.7.99.3 included with EC 1.7.2.1
EC 1.7.99.4 transferred, now EC 1.7.1.1, EC 1.7.1.2, EC 1.7.1.3, EC 1.7.5.1, EC 1.7.7.2 and EC 1.9.6.1
EC 1.7.99.5 deleted, now included with EC 1.5.1.20
EC 1.7.99.6 transferred now EC 1.7.2.4
EC 1.7.99.7 transferred now EC 1.7.2.5
EC 1.7.99.8 transferred, now EC 1.7.2.8
EC 1.8 Acting on a sulfur group of donors

EC 1.8.1 With NAD+ or NADP+ as acceptor

EC 1.8.1.1 deleted
EC 1.8.1.2 assimilatory sulfite reductase (NADPH)
EC 1.8.1.3 deleted
EC 1.8.1.4 dihydrolipoyl dehydrogenase
EC 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)
EC 1.8.1.6 cystine reductase
EC 1.8.1.7 glutathione-disulfide reductase
EC 1.8.1.8 protein-disulfide reductase
EC 1.8.1.9 thioredoxin-disulfide reductase
EC 1.8.1.10 CoA-glutathione reductase
EC 1.8.1.11 asparagusate reductase
EC 1.8.1.12 trypanothione-disulfide reductase
EC 1.8.1.13 bis-γ-glutamylcystine reductase
EC 1.8.1.14 CoA-disulfide reductase
EC 1.8.1.15 mycothione reductase
EC 1.8.1.16 glutathione amide reductase
EC 1.8.1.17 dimethylsulfone reductase
EC 1.8.1.18 NAD(P)H sulfur oxidoreductase (CoA-dependent)
EC 1.8.1.19 sulfide dehydrogenase
EC 1.8.1.20 4,4'-dithiodibutanoate disulfide reductase
EC 1.8.1.21 dissimilatory dimethyldisulfide reductase
EC 1.8.1.22 dissimilatory sulfite reductase system
EC 1.8.2 With a cytochrome as acceptor
EC 1.8.2.1 sulfite dehydrogenase (cytochrome)
EC 1.8.2.2 thiosulfate dehydrogenase
EC 1.8.2.3 sulfide-cytochrome-c reductase (flavocytochrome c)
EC 1.8.2.4 dimethyl sulfide:cytochrome c2 reductase
EC 1.8.2.5 thiosulfate reductase (cytochrome)
EC 1.8.2.6 S-disulfanyl-L-cysteine oxidoreductase
EC 1.8.2.7 thiocyanate desulfurase
EC 1.8.3 With oxygen as acceptor
EC 1.8.3.1 sulfite oxidase
EC 1.8.3.2 thiol oxidase
EC 1.8.3.3 glutathione oxidase
EC 1.8.3.4 methanethiol oxidase
EC 1.8.3.5 prenylcysteine oxidase
EC 1.8.3.6 farnesylcysteine lyase
EC 1.8.3.7 formylglycine-generating enzyme
EC 1.8.4 With a disulfide as acceptor
EC 1.8.4.1 glutathione—homocystine transhydrogenase
EC 1.8.4.2 protein-disulfide reductase (glutathione)
EC 1.8.4.3 glutathione—CoA-glutathione transhydrogenase
EC 1.8.4.4 glutathione—cystine transhydrogenase
EC 1.8.4.5 now EC 1.8.4.13 and EC 1.8.4.14
EC 1.8.4.6 now EC 1.8.4.11
EC 1.8.4.7 enzyme-thiol transhydrogenase (glutathione-disulfide)
EC 1.8.4.8 phosphoadenylyl-sulfate reductase (thioredoxin)
EC 1.8.4.9 adenylyl-sulfate reductase (glutathione)
EC 1.8.4.10 adenylyl-sulfate reductase (thioredoxin)
EC 1.8.4.11 peptide-methionine (S)-S-oxide reductase
EC 1.8.4.12 peptide-methionine (R)-S-oxide reductase
EC 1.8.4.13 L-methionine (S)-S-oxide reductase
EC 1.8.4.14 L-methionine (R)-S-oxide reductase
EC 1.8.4.15 protein dithiol oxidoreductase (disulfide-forming)
EC 1.8.4.16 thioredoxin:protein disulfide reductase
EC 1.8.5 With a quinone or similar compound as acceptor
EC 1.8.5.1 glutathione dehydrogenase (ascorbate)
EC 1.8.5.2 thiosulfate dehydrogenase (quinone)
EC 1.8.5.3 respiratory dimethylsulfoxide reductase
EC 1.8.5.4 bacterial sulfide:quinone reductase
EC 1.8.5.5 thiosulfate reductase (quinone)
EC 1.8.5.6 sulfite dehydrogenase (quinone)
EC 1.8.5.7 glutathionyl-hydroquinone reductase
EC 1.8.5.8 eukaryotic sulfide quinone oxidoreductase
EC 1.8.5.9 protein dithiol:quinone oxidoreductase DsbB
EC 1.8.5.10 [DsrC]-trisulfide reductase
EC 1.8.6 With an nitrogenous group as acceptor
EC 1.8.6.1 deleted, included in EC 2.5.1.18
EC 1.8.7 With an iron-sulfur protein as acceptor
EC 1.8.7.1 assimilatory sulfite reductase (ferredoxin)
EC 1.8.7.2 ferredoxin:thioredoxin reductase
EC 1.8.7.3 ferredoxin:CoB-CoM heterodisulfide reductase
EC 1.8.98 With other, known, physiological acceptors
EC 1.8.98.1 dihydromethanophenazine:CoB-CoM heterodisulfide reductase
EC 1.8.98.2 sulfiredoxin
EC 1.8.98.3 sulfite reductase (coenzyme F420)
EC 1.8.98.4 coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase
EC 1.8.98.5 H2:CoB-CoM heterodisulfide,ferredoxin reductase
EC 1.8.98.6 formate:CoB-CoM heterodisulfide,ferredoxin reductase
EC 1.8.98.7 cysteine-type anaerobic sulfatase-maturating enzyme
EC 1.8.99 With unknown physiological acceptors
EC 1.8.99.1 deleted now covered by EC 1.8.1.2 and EC 1.8.7.1
EC 1.8.99.2 adenylyl-sulfate reductase
EC 1.8.99.3 deleted
EC 1.8.99.4 now EC 1.8.4.8
EC 1.8.99.5 transferred now EC 1.8.1.22
EC 1.8.99.5 dissimilatory sulfite reductase
EC 1.9 Acting on a heme group of donors

EC 1.9.3 With oxygen as acceptor
EC 1.9.3.1 now EC 7.1.1.9
EC 1.9.3.2 included with EC 1.7.2.1
EC 1.9.6 With a nitrogenous group as acceptor

EC 1.9.6.1 nitrate reductase (cytochrome)
EC 1.9.98 With other, known, physiological acceptors
EC 1.9.98.1 iron—cytochrome-c reductase
EC 1.9.99 With unknown physiological acceptors
EC 1.9.99.1 transferred, now EC 1.9.98.1
EC 1.10 Acting on diphenols and related substances as donors

EC 1.10.1 With NAD+ or NADP+ as acceptor

EC 1.10.1.1 trans-acenaphthene-1,2-diol dehydrogenase
EC 1.10.2 With a cytochrome as acceptor
EC 1.10.2.1 deleted, now covered byEC 7.2.1.3
EC 1.10.2.2 transferred now EC 7.1.1.8
EC 1.10.3 With oxygen as acceptor
EC 1.10.3.1 catechol oxidase
EC 1.10.3.2 laccase
EC 1.10.3.3 L-ascorbate oxidase
EC 1.10.3.4 o-aminophenol oxidase
EC 1.10.3.5 3-hydroxyanthranilate oxidase
EC 1.10.3.6 rifamycin-B oxidase
EC 1.10.3.7 now EC 1.21.3.4
EC 1.10.3.8 now EC 1.21.3.5
EC 1.10.3.9 photosystem II
EC 1.10.3.10 transferred now EC 7.1.1.3
EC 1.10.3.11 ubiquinol oxidase (non-electrogenic)
EC 1.10.3.12 transferred now EC 7.1.1.5
EC 1.10.3.13 transferred now EC 7.1.1.4
EC 1.10.3.14 transferred now EC 7.1.1.7
EC 1.10.3.15 grixazone synthase
EC 1.10.3.16 dihydrophenazinedicarboxylate synthase
EC 1.10.3.17 superoxide oxidase
EC 1.10.5 With a quinone or related compound as acceptor
EC 1.10.5.1 ribosyldihydronicotinamide dehydrogenase (quinone)
EC 1.10.9 With a copper protein as acceptor
EC 1.10.9.1 transferred now EC 7.1.1.6
EC 1.10.99 With unknown physiological acceptors
EC 1.10.99.1 transferred now EC 1.10.9.1
EC 1.10.99.2 transferred now EC 1.10.5.1
EC 1.10.99.3 transferred now EC 1.23.5.1
EC 1.11 Acting on a peroxide as acceptor

EC 1.11.1 Peroxidases

EC 1.11.1.1 NADH peroxidase
EC 1.11.1.2 NADPH peroxidase
EC 1.11.1.3 fatty-acid peroxidase
EC 1.11.1.4 now EC 1.13.11.11
EC 1.11.1.5 cytochrome-c peroxidase
EC 1.11.1.6 catalase
EC 1.11.1.7 peroxidase
EC 1.11.1.8 iodide peroxidase
EC 1.11.1.9 glutathione peroxidase
EC 1.11.1.10 chloride peroxidase
EC 1.11.1.11 L-ascorbate peroxidase
EC 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase
EC 1.11.1.13 manganese peroxidase
EC 1.11.1.14 lignin peroxidase
EC 1.11.1.15 now described by EC 1.11.1.24, EC 1.11.1.25, EC 1.11.1.26, EC 1.11.1.27, EC 1.11.1.28, and EC 1.11.1.29
EC 1.11.1.16 versatile peroxidase
EC 1.11.1.17 glutathione amide-dependent peroxidase
EC 1.11.1.18 bromide peroxidase
EC 1.11.1.19 dye decolorizing peroxidase
EC 1.11.1.20 prostamide/prostaglandin F2α synthase
EC 1.11.1.21 catalase-peroxidase
EC 1.11.1.22 hydroperoxy fatty acid reductase
EC 1.11.1.23 (S)-2-hydroxypropylphosphonic acid epoxidase
EC 1.11.1.24 thioredoxin-dependent peroxiredoxin
EC 1.11.1.25 glutaredoxin-dependent peroxiredoxin
EC 1.11.1.26 NADH-dependent peroxiredoxin
EC 1.11.1.27 glutathione-dependent peroxiredoxin
EC 1.11.1.28 lipoyl-dependent peroxiredoxin
EC 1.11.1.29 mycoredoxin-dependent peroxiredoxin
EC 1.11.2 With H2O2 as acceptor, one oxygen atom of which is incorporated into the product
EC 1.11.2.1 unspecific peroxygenase
EC 1.11.2.2 myeloperoxidase
EC 1.11.2.3 plant seed peroxygenase
EC 1.11.2.4 fatty-acid peroxygenase
EC 1.11.2.5 3-methyl-L-tyrosine peroxygenase
EC 1.11.2.6 L-tyrosine peroxygenase
EC 1.12 Acting on hydrogen as donor

EC 1.12.1 With NAD+ or NADP+ as acceptor

EC 1.12.1.1 now EC 1.18.99.1
EC 1.12.1.2 hydrogen dehydrogenase
EC 1.12.1.3 hydrogen dehydrogenase (NADP+)
EC 1.12.1.4 hydrogenase (NAD+, ferredoxin)
EC 1.12.1.5 hydrogen dehydrogenase [NAD(P)+]
EC 1.12.2 With a cytochrome as acceptor
EC 1.12.2.1 cytochrome-c3 hydrogenase
EC 1.12.5 With a quinone or similar compound as acceptor
EC 1.12.5.1 hydrogen:quinone oxidoreductase
EC 1.12.7 With an iron-sulfur protein as acceptor
EC 1.12.7.1 now EC 1.18.99.1
EC 1.12.7.2 ferredoxin hydrogenase
EC 1.12.98 With other, known, physiological acceptors
EC 1.12.98.1 coenzyme F420 hydrogenase
EC 1.12.98.2 5,10-methenyltetrahydromethanopterin hydrogenase
EC 1.12.98.3 Methanosarcina-phenazine hydrogenase
EC 1.12.98.4 sulfhydrogenase
EC 1.12.99 With unknown physiological acceptors
EC 1.12.99.1 now EC 1.12.98.1
EC 1.12.99.2 deleted, composed of EC 1.12.98.3 and EC 1.8.98.1
EC 1.12.99.3 now EC 1.12.5.1
EC 1.12.99.4 now EC 1.12.98.2
EC 1.12.99.5 deleted, identical to EC 1.13.11.47
EC 1.12.99.6 hydrogenase (acceptor)
EC 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

EC 1.13.11 With incorporation of two atoms of oxygen

EC 1.13.11.1 catechol 1,2-dioxygenase
EC 1.13.11.2 catechol 2,3-dioxygenase
EC 1.13.11.3 protocatechuate 3,4-dioxygenase
EC 1.13.11.4 gentisate 1,2-dioxygenase
EC 1.13.11.5 homogentisate 1,2-dioxygenase
EC 1.13.11.6 3-hydroxyanthranilate 3,4-dioxygenase
EC 1.13.11.7 deleted
EC 1.13.11.8 protocatechuate 4,5-dioxygenase
EC 1.13.11.9 2,5-dihydroxypyridine 5,6-dioxygenase
EC 1.13.11.10 7,8-dihydroxykynurenate 8,8a-dioxygenase
EC 1.13.11.11 tryptophan 2,3-dioxygenase
EC 1.13.11.12 linoleate 13S-lipoxygenase
EC 1.13.11.13 deleted
EC 1.13.11.14 2,3-dihydroxybenzoate 3,4-dioxygenase
EC 1.13.11.15 3,4-dihydroxyphenylacetate 2,3-dioxygenase
EC 1.13.11.16 3-carboxyethylcatechol 2,3-dioxygenase
EC 1.13.11.17 indole 2,3-dioxygenase
EC 1.13.11.18 sulfur dioxygenase
EC 1.13.11.19 cysteamine dioxygenase
EC 1.13.11.20 cysteine dioxygenase
EC 1.13.11.21 now EC 1.14.99.36
EC 1.13.11.22 caffeate 3,4-dioxygenase
EC 1.13.11.23 2,3-dihydroxyindole 2,3-dioxygenase
EC 1.13.11.24 quercetin 2,3-dioxygenase
EC 1.13.11.25 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase
EC 1.13.11.26 peptide-tryptophan 2,3-dioxygenase
EC 1.13.11.27 4-hydroxyphenylpyruvate dioxygenase
EC 1.13.11.28 2,3-dihydroxybenzoate 2,3-dioxygenase
EC 1.13.11.29 stizolobate synthase
EC 1.13.11.30 stizolobinate synthase
EC 1.13.11.31 arachidonate 12-lipoxygenase
EC 1.13.11.32 transferred now EC 1.13.12.16
EC 1.13.11.33 arachidonate 15-lipoxygenase
EC 1.13.11.34 arachidonate 5-lipoxygenase
EC 1.13.11.35 pyrogallol 1,2-oxygenase
EC 1.13.11.36 chloridazon-catechol dioxygenase
EC 1.13.11.37 hydroxyquinol 1,2-dioxygenase
EC 1.13.11.38 isoeugenol monooxygenase
EC 1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase
EC 1.13.11.40 arachidonate 8-lipoxygenase
EC 1.13.11.41 2,4'-dihydroxyacetophenone dioxygenase
EC 1.13.11.42 deleted
EC 1.13.11.43 lignostilbene αβ-dioxygenase
EC 1.13.11.44 deleted covered by EC 1.13.11.60 and EC 5.4.4.6
EC 1.13.11.45 linoleate 11-lipoxygenase
EC 1.13.11.46 4-hydroxymandelate synthase
EC 1.13.11.47 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
EC 1.13.11.48 3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase
EC 1.13.11.49 chlorite O2-lyase
EC 1.13.11.50 acetylacetone-cleaving enzyme
EC 1.13.11.51 9-cis-epoxycarotenoid dioxygenase
EC 1.13.11.52 indoleamine 2,3-dioxygenase
EC 1.13.11.53 acireductone dioxygenase (Ni2+-requiring)
EC 1.13.11.54 acireductone dioxygenase [iron(II)-requiring]
EC 1.13.11.55 sulfur oxygenase/reductase
EC 1.13.11.56 1,2-dihydroxynaphthalene dioxygenase
EC 1.13.11.57 gallate dioxygenase
EC 1.13.11.58 linoleate 9S-lipoxygenase
EC 1.13.11.59 torulene dioxygenase
EC 1.13.11.60 linoleate 8R-lipoxygenase
EC 1.13.11.61 linolenate 9R-lipoxygenase
EC 1.13.11.62 linoleate 10R-lipoxygenase
EC 1.13.11.63 β-carotene 15,15'-dioxygenase
EC 1.13.11.64 5-nitrosalicylate dioxygenase
EC 1.13.11.65 carotenoid isomerooxygenase
EC 1.13.11.66 hydroquinone 1,2-dioxygenase
EC 1.13.11.67 8'-apo-β-carotenoid 14',13'-cleaving dioxygenase
EC 1.13.11.68 9-cis-β-carotene 9',10'-cleaving dioxygenase
EC 1.13.11.69 carlactone synthase
EC 1.13.11.70 all-trans-10'-apo-β-carotenal 13,14-cleaving dioxygenase
EC 1.13.11.71 carotenoid-9',10'-cleaving dioxygenase
EC 1.13.11.72 2-hydroxyethylphosphonate dioxygenase
EC 1.13.11.73 methylphosphonate synthase
EC 1.13.11.74 2-aminophenol 1,6-dioxygenase
EC 1.13.11.75 all-trans-8'-apo-β-carotenal 15,15'-oxygenase
EC 1.13.11.76 2-amino-5-chlorophenol 1,6-dioxygenase
EC 1.13.11.77 oleate 10S-lipoxygenase
EC 1.13.11.78 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming)
EC 1.13.11.79 aerobic 5,6-dimethylbenzimidazole synthase
EC 1.13.11.80 (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase
EC 1.13.11.81 7,8-dihydroneopterin oxygenase
EC 1.13.11.82 8'-apo-carotenoid 13,14-cleaving dioxygenase
EC 1.13.11.83 4-hydroxy-3-prenylphenylpyruvate oxygenase
EC 1.13.11.84 crocetin dialdehyde synthase
EC 1.13.11.85 exo-cleaving rubber dioxygenase
EC 1.13.11.86 5-aminosalicylate 1,2-dioxygenase
EC 1.13.11.87 endo-cleaving rubber dioxygenase
EC 1.13.11.88 isoeugenol monooxygenase
EC 1.13.11.89 hydroxymethylphosphonate dioxygenase
EC 1.13.11.90 [1-hydroxy-2-(trimethylamino)ethyl]phosphonate dioxygenase (glycine-betaine-forming)
EC 1.13.11.91 3-mercaptopropionate dioxygenase
EC 1.13.11.92 fatty acid α-dioxygenase
EC 1.13.11.93 2-oxoadipate dioxygenase/decarboxylase
EC 1.13.11.94 4-vinylguaiacol dioxygenase
EC 1.13.11.95 2-oxoethane-1-sulfonamide synthase
EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
EC 1.13.12.1 arginine 2-monooxygenase
EC 1.13.12.2 lysine 2-monooxygenase
EC 1.13.12.3 tryptophan 2-monooxygenase
EC 1.13.12.4 lactate 2-monooxygenase
EC 1.13.12.5 Renilla-type luciferase
EC 1.13.12.6 Cypridina-luciferin 2-monooxygenase
EC 1.13.12.7 firefly luciferase
EC 1.13.12.8 Watasenia-luciferin 2-monooxygenase
EC 1.13.12.9 phenylalanine 2-monooxygenase
EC 1.13.12.10 lysine 6-monooxygenase
EC 1.13.12.10 Deleted, covered by EC 1.14.13.59
EC 1.13.12.11 now EC 1.14.13.8
EC 1.13.12.12 transferred, now EC 1.13.11.67
EC 1.13.12.13 Oplophorus-luciferin 2-monooxygenase
EC 1.13.12.14 transferred now EC 1.14.13.122
EC 1.13.12.15 3,4-dihydroxyphenylalanine oxidative deaminase
EC 1.13.12.16 nitronate monooxygenase
EC 1.13.12.17 dichloroarcyriaflavin A synthase
EC 1.13.12.18 dinoflagellate luciferase
EC 1.13.12.19 2-oxuglutarate dioxygenase (ethylene-forming)
EC 1.13.12.20 noranthrone monooxygenase
EC 1.13.12.21 tetracenomycin-F1 monooxygenase
EC 1.13.12.22 deoxynogalonate monooxygenase
EC 1.13.12.23 4-hydroxy-3-prenylbenzoate synthase
EC 1.13.12.24 calcium-regulated photoprotein
EC 1.13.99 Miscellaneous
EC 1.13.99.1 inositol oxygenase
EC 1.13.99.2 now EC 1.14.12.10
EC 1.13.99.3 tryptophan 2'-dioxygenase
EC 1.13.99.4 now EC 1.14.12.9
EC 1.13.99.5 now EC 1.13.11.47
EC 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

EC 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

EC 1.14.11.1 γ-butyrobetaine dioxygenase
EC 1.14.11.2 procollagen-proline 4-dioxygenase
EC 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase
EC 1.14.11.4 procollagen-lysine 5-dioxygenase
EC 1.14.11.5 deleted, included in EC 1.14.11.6
EC 1.14.11.6 thymine dioxygenase
EC 1.14.11.7 procollagen-proline 3-dioxygenase
EC 1.14.11.8 trimethyllysine dioxygenase
EC 1.14.11.9 flavanone 3-dioxygenase
EC 1.14.11.10 pyrimidine-deoxynucleoside 1'-dioxygenase
EC 1.14.11.11 hyoscyamine (6S)-dioxygenase
EC 1.14.11.12 gibberellin-44 dioxygenase
EC 1.14.11.13 gibberellin 2β-dioxygenase
EC 1.14.11.14 transferred now EC 1.14.20.13
EC 1.14.11.15 gibberellin 3β-dioxygenase
EC 1.14.11.16 peptide-aspartate β-dioxygenase
EC 1.14.11.17 taurine dioxygenase
EC 1.14.11.18 phytanoyl-CoA dioxygenase
EC 1.14.11.19 transferred now EC 1.14.20.4
EC 1.14.11.20 deacetoxyvindoline 4-hydroxylase
EC 1.14.11.21 clavaminate synthase
EC 1.14.11.22 transferred now EC 1.14.20.5
EC 1.14.11.23 transferred now EC 1.14.20.6
EC 1.14.11.24 2'-deoxymugineic-acid 2'-dioxygenase
EC 1.14.11.25 mugineic-acid 3-dioxygenase
EC 1.14.11.26 deacetoxycephalosporin-C hydroxylase
EC 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase
EC 1.14.11.28 proline 3-hydroxylase
EC 1.14.11.29 hypoxia-inducible factor-proline dioxygenase
EC 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase
EC 1.14.11.31 thebaine 6-O-demethylase
EC 1.14.11.32 codeine 3-O-demethylase
EC 1.14.11.33 DNA oxidative demethylase
EC 1.14.11.34 transferred now EC 1.14.20.7
EC 1.14.11.35 1-deoxypentalenic acid 11β-hydroxylase
EC 1.14.11.36 pentalenolactone F synthase
EC 1.14.11.37 kanamycin B dioxygenase
EC 1.14.11.38 verruculogen synthase
EC 1.14.11.39 L-asparagine hydroxylase
EC 1.14.11.40 enduracididine β-hydroxylase
EC 1.14.11.41 L-arginine hydroxylase
EC 1.14.11.42 tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase
EC 1.14.11.43 (S)-dichlorprop dioxygenase (2-oxoglutarate)
EC 1.14.11.44 (R)-dichlorprop dioxygenase (2-oxoglutarate)
EC 1.14.11.45 L-isoleucine 4-hydroxylase
EC 1.14.11.46 2-aminoethylphosphonate dioxygenase
EC 1.14.11.47 50S ribosomal protein L16 3-hydroxylase
EC 1.14.11.48 xanthine dioxygenase
EC 1.14.11.49 uridine-5'-phosphate dioxygenase
EC 1.14.11.50 transferred now EC 1.14.20.8
EC 1.14.11.51 DNA N6-methyladenine demethylase
EC 1.14.11.52 validamycin A dioxygenase
EC 1.14.11.53 mRNA N6-methyladenine demethylase
EC 1.14.11.54 mRNA N1-methyladenine demethylase
EC 1.14.11.55 ectoine hydroxylase
EC 1.14.11.56 L-proline cis-4-hydroxylase
EC 1.14.11.57 L-proline trans-4-hydroxylase
EC 1.14.11.58 ornithine lipid ester-linked acyl 2-hydroxylase
EC 1.14.11.59 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase
EC 1.14.11.60 scopoletin 8-hydroxylase
EC 1.14.11.61 feruloyl-CoA 6-hydroxylase
EC 1.14.11.62 trans-4-coumaroyl-CoA 2-hydroxylase
EC 1.14.11.63 peptidyl-lysine (3S)-dioxygenase
EC 1.14.11.64 glutarate dioxygenase
EC 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase
EC 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase
EC 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase
EC 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase
EC 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase
EC 1.14.11.70 7-deoxycylindrospermopsin hydroxylase
EC 1.14.11.71 methylphosphonate hydroxylase
EC 1.14.11.72 [2-(trimethylamino)ethyl]phosphonate dioxygenase
EC 1.14.11.76 L-glutamate 3(R)-hydroxylase
EC 1.14.11.73 [protein]-arginine 3-hydroxylase
EC 1.14.11.74 L-isoleucine 31-dioxygenase
EC 1.14.11.75 31-hydroxy-L-isoleucine 4-dioxygenase
EC 1.14.11.76 L-glutamate 3(R)-hydroxylase
EC 1.14.11.77 alkyl sulfatase
EC 1.14.11.78 (R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase
EC 1.14.11.79 protein-L-histidine (3S)-3-hydroxylase
EC 1.14.11.80 methylcytosine dioxygenase
EC 1.14.11.81 (–)-cyclopenine synthase
EC 1.14.11.82 5-dehydro-6-demethoxyfumagillol dioxygenase
EC 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor
EC 1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
EC 1.14.12.2 now EC 1.14.13.35
EC 1.14.12.3 benzene 1,2-dioxygenase
EC 1.14.12.4 transferred now EC 1.14.13.242
EC 1.14.12.5 transferred now EC 1.14.13.241
EC 1.14.12.6 now EC 1.14.13.66
EC 1.14.12.7 phthalate 4,5-dioxygenase
EC 1.14.12.8 4-sulfobenzoate 3,4-dioxygenase
EC 1.14.12.9 4-chlorophenylacetate 3,4-dioxygenase
EC 1.14.12.10 benzoate 1,2-dioxygenase
EC 1.14.12.11 toluene dioxygenase
EC 1.14.12.12 naphthalene 1,2-dioxygenase
EC 1.14.12.13 2-halobenzoate 1,2-dioxygenase
EC 1.14.12.14 2-aminobenzenesulfonate 2,3-dioxygenase
EC 1.14.12.15 terephthalate 1,2-dioxygenase
EC 1.14.12.16 2-hydroxyquinoline 5,6-dioxygenase
EC 1.14.12.17 nitric oxide dioxygenase
EC 1.14.12.18 biphenyl 2,3-dioxygenase
EC 1.14.12.19 3-phenylpropionate dioxygenase
EC 1.14.12.20 transferred now EC 1.14.15.17
EC 1.14.12.21 transferred now EC 1.14.13.208
EC 1.14.12.22 carbazole 1,9a-dioxygenase
EC 1.14.12.23 nitroarene dioxygenase
EC 1.14.12.24 2,4-dinitrotoluene dioxygenase
EC 1.14.12.25 p-cumate 2,3-dioxygenase
EC 1.14.12.26 chlorobenzene dioxygenase
EC 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen
EC 1.14.13.1 salicylate 1-monooxygenase
EC 1.14.13.2 4-hydroxybenzoate 3-monooxygenase
EC 1.14.13.3 transferred now EC 1.14.14.9
EC 1.14.13.4 melilotate 3-monooxygenase
EC 1.14.13.5 imidazoleacetate 4-monooxygenase
EC 1.14.13.6 orcinol 2-monooxygenase
EC 1.14.13.7 phenol 2-monooxygenase (NADPH)
EC 1.14.13.8 flavin-containing monooxygenase
EC 1.14.13.9 kynurenine 3-monooxygenase
EC 1.14.13.10 2,6-dihydroxypyridine 3-monooxygenase
EC 1.14.13.11 transferred now EC 1.14.14.91
EC 1.14.13.12 transferred now EC 1.14.14.92
EC 1.14.13.13 transferred, now EC 1.14.15.18
EC 1.14.13.14 trans-cinnamate 2-monooxygenase
EC 1.14.13.15 transferred now EC 1.14.15.15
EC 1.14.13.16 cyclopentanone monooxygenase
EC 1.14.13.17 transferred now EC 1.14.14.23
EC 1.14.13.18 4-hydroxyphenylacetate 1-monooxygenase
EC 1.14.13.19 taxifolin 8-monooxygenase
EC 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
EC 1.14.13.21 transferred now EC 1.14.14.82
EC 1.14.13.22 cyclohexanone monooxygenase
EC 1.14.13.23 3-hydroxybenzoate 4-monooxygenase
EC 1.14.13.24 3-hydroxybenzoate 6-monooxygenase
EC 1.14.13.25 methane monooxygenase (soluble)
EC 1.14.13.26 transferred now EC 1.14.18.4
EC 1.14.13.27 4-aminobenzoate 1-monooxygenase
EC 1.14.13.28 transferred now EC 1.14.14.93
EC 1.14.13.29 4-nitrophenol 2-monooxygenase
EC 1.14.13.30 transferred now EC 1.14.14.94
EC 1.14.13.31 2-nitrophenol 2-monooxygenase
EC 1.14.13.32 albendazole monooxygenase (flavin-containing)
EC 1.14.13.33 4-hydroxybenzoate 3-monooxygenase [NAD(P)H]
EC 1.14.13.34 leukotriene-E4 20-monooxygenase
EC 1.14.13.35 anthranilate 3-monooxygenase (deaminating)
EC 1.14.13.36 transferred now EC 1.14.14.96
EC 1.14.13.37 transferred now EC 1.14.14.97
EC 1.14.13.38 anhydrotetracycline 6-monooxygenase
EC 1.14.13.39 nitric-oxide synthase (NADPH)
EC 1.14.13.40 anthraniloyl-CoA monooxygenase
EC 1.14.13.41 now EC 1.14.14.36
EC 1.14.13.42 deleted covered by EC 1.14.13.68
EC 1.14.13.43 questin monooxygenase
EC 1.14.13.44 2-hydroxybiphenyl 3-monooxygenase
EC 1.14.13.45 now EC 1.14.18.2
EC 1.14.13.46 (–)-menthol monooxygenase
EC 1.14.13.47 transferred now EC 1.14.14.99
EC 1.14.13.48 transferred now EC 1.14.14.51
EC 1.14.13.49 transferred now EC 1.14.14.52
EC 1.14.13.50 pentachlorophenol monooxygenase
EC 1.14.13.51 6-oxocineole dehydrogenase
EC 1.14.13.52 transferred now EC 1.14.14.88
EC 1.14.13.53 transferred now EC 1.14.14.89
EC 1.14.13.54 ketosteroid monooxygenase
EC 1.14.13.55 transferred now EC 1.14.14.98
EC 1.14.13.56 transferred now EC 1.14.14.100
EC 1.14.13.57 transferred now EC 1.14.14.101
EC 1.14.13.58 benzoyl-CoA 3-monooxygenase
EC 1.14.13.59 L-lysine 6-monooxygenase (NADPH)
EC 1.14.13.60 transferred now EC 1.14.13.100
EC 1.14.13.61 2-hydroxyquinoline 8-monooxygenase
EC 1.14.13.62 4-hydroxyquinoline 3-monooxygenase
EC 1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase
EC 1.14.13.64 4-hydroxybenzoate 1-hydroxylase
EC 1.14.13.65 deleted
EC 1.14.13.66 2-hydroxycyclohexanone 2-monooxygenase
EC 1.14.13.67 transferred now EC 1.14.14.55
EC 1.14.13.68 now EC 1.14.14.37
EC 1.14.13.69 alkene monooxygenase
EC 1.14.13.70 transferred now EC 1.14.14.154
EC 1.14.13.71 transferred now EC 1.14.14.102
EC 1.14.13.72 transferred now EC 1.14.18.9
EC 1.14.13.73 transferred now EC 1.14.14.103
EC 1.14.13.74 transferred now EC 1.14.14.85
EC 1.14.13.75 transferred now EC 1.14.14.104
EC 1.14.13.76 transferred now EC 1.14.14.105
EC 1.14.13.77 transferred now EC 1.14.14.106
EC 1.14.13.78 transferred now EC 1.14.14.86
EC 1.14.13.79 transferred now EC 1.14.14.107
EC 1.14.13.80 transferred now EC 1.14.14.53
EC 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
EC 1.14.13.82 vanillate monooxygenase
EC 1.14.13.83 precorrin-3B synthase
EC 1.14.13.84 4-hydroxyacetophenone monooxygenase
EC 1.14.13.85 transferred now EC 1.14.14.135
EC 1.14.13.86 deleted
EC 1.14.13.87 transferred now EC 1.14.14.140
EC 1.14.13.88 transferred now EC 1.14.14.81
EC 1.14.13.89 transferred now EC 1.14.14.90
EC 1.14.13.90 now EC 1.14.15.21
EC 1.14.13.91 transferred now EC 1.14.14.136
EC 1.14.13.92 phenylacetone monooxygenase
EC 1.14.13.93 transferred now EC 1.14.14.137
EC 1.14.13.94 transferred now EC 1.14.14.138
EC 1.14.13.95 transferred now EC 1.14.18.8
EC 1.14.13.96 transferred now EC 1.14.14.139
EC 1.14.13.97 transferred now EC 1.14.14.57
EC 1.14.13.98 transferred now EC 1.14.14.25
EC 1.14.13.99 transferred now EC 1.14.14.26
EC 1.14.13.100 transferred, now EC 1.14.14.29
EC 1.14.13.101 senecionine N-oxygenase
EC 1.14.13.102 transferred now EC 1.14.14.141
EC 1.14.13.103 transferred now EC 1.14.14.142
EC 1.14.13.104 transferred now EC 1.14.14.143
EC 1.14.13.105 monocyclic monoterpene ketone monooxygenase
EC 1.14.13.106 transferred, now EC 1.14.15.39
EC 1.14.13.107 limonene 1,2-monooxygenase
EC 1.14.13.108 transferred now EC 1.14.14.144
EC 1.14.13.109 transferred now EC 1.14.14.145
EC 1.14.13.110 transferred now EC 1.14.14.146
EC 1.14.13.111 methanesulfonate monooxygenase (NADH)
EC 1.14.13.112 transferred now EC 1.14.14.147
EC 1.14.13.113 FAD-dependent urate hydroxylase
EC 1.14.13.114 6-hydroxynicotinate 3-monooxygenase
EC 1.14.13.115 transferred now EC 1.14.14.148
EC 1.14.13.116 transferred now EC 1.14.14.174
EC 1.14.13.117 transferred now EC 1.14.14.39
EC 1.14.13.118 transferred now EC 1.14.14.38
EC 1.14.13.119 transferred now EC 1.14.14.149
EC 1.14.13.120 transferred now EC 1.14.14.150
EC 1.14.13.121 transferred now EC 1.14.14.151
EC 1.14.13.122 chlorophyllide-a oxygenase
EC 1.14.13.123 transferred now EC 1.14.14.95
EC 1.14.13.124 transferred now EC 1.14.14.40
EC 1.14.13.125 >transferred, now EC 1.14.14.156
EC 1.14.13.126 transferred now EC 1.14.15.16
EC 1.14.13.159 transferred now EC 1.14.14.24
EC 1.14.13.127 3-(3-hydroxyphenyl)propanoate hydroxylase
EC 1.14.13.128 7-methylxanthine demethylase
EC 1.14.13.129 transferred now EC 1.14.15.24
EC 1.14.13.130 pyrrole-2-carboxylate monooxygenase
EC 1.14.13.131 dimethyl-sulfide monooxygenase
EC 1.14.13.132 transferred now EC 1.14.14.17
EC 1.14.13.133 transferred now EC 1.14.15.32
EC 1.14.13.134 transferred now EC 1.14.14.152
EC 1.14.13.135 1-hydroxy-2-naphthoate hydroxylase
EC 1.14.13.136 transferred now EC 1.14.14.87
EC 1.14.13.137 transferred now EC 1.14.14.153
EC 1.14.13.138 transferred, now EC 1.14.14.157
EC 1.14.13.139 transferred now EC 1.14.14.109
EC 1.14.13.140 transferred now EC 1.14.14.110
EC 1.14.13.141 transferred now EC 1.14.15.29
EC 1.14.13.142 transferred now EC 1.14.15.30
EC 1.14.13.143 transferred now EC 1.14.14.76
EC 1.14.13.144 transferred now EC 1.14.14.111
EC 1.14.13.145 transferred now EC 1.14.14.112
EC 1.14.13.146 taxoid 14β-hydroxylase
EC 1.14.13.147 taxoid 7β-hydroxylase
EC 1.14.13.147 transferred now EC 1.14.14.182
EC 1.14.13.148 trimethylamine monooxygenase
EC 1.14.13.149 phenylacetyl-CoA 1,2-epoxidase
EC 1.14.13.150 transferred now EC 1.14.14.113
EC 1.14.13.151 transferred now EC 1.14.14.84
EC 1.14.13.152 transferred now EC 1.14.14.83
EC 1.14.13.153 (+)-sabinene 3-hydroxylase
EC 1.14.13.154 erythromycin 12-hydroxylase
EC 1.14.13.155 α-pinene monooxygenase
EC 1.14.13.156 transferred now EC 1.14.14.133
EC 1.14.13.157 transferred now EC 1.14.14.56
EC 1.14.13.158 transferred now EC 1.14.14.114
EC 1.14.13.159 vitamin D 25-hydroxylase
EC 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
EC 1.14.13.161 (+)-camphor 6-exo-hydroxylase
EC 1.14.13.162 transferred now EC 1.14.14.108
EC 1.14.13.163 6-hydroxy-3-succinoylpyridine 3-monooxygenase
EC 1.14.13.164 transferred now EC 1.13.11.65
EC 1.14.13.165 transferred, now EC 1.14.14.47
EC 1.14.13.166 4-nitrocatechol 4-monooxygenase
EC 1.14.13.167 4-nitrophenol 4-monooxygenase
EC 1.14.13.168 indole-3-pyruvate monooxygenase
EC 1.14.13.169 transferred now EC 1.14.18.5
EC 1.14.13.170 pentalenolactone D synthase
EC 1.14.13.171 neopentalenolactone D synthase
EC 1.14.13.172 salicylate 5-hydroxylase
EC 1.14.13.173 transferred now EC 1.14.14.115
EC 1.14.13.174 transferred now EC 1.14.14.116
EC 1.14.13.175 transferred now EC 1.14.14.117
EC 1.14.13.176 transferred now EC 1.14.14.118
EC 1.14.13.177 transferred now EC 1.14.14.119
EC 1.14.13.178 methylxanthine N1-demethylase
EC 1.14.13.179 methylxanthine N3-demethylase
EC 1.14.13.180 aklavinone 12-hydroxylase
EC 1.14.13.181 13-deoxydaunorubicin hydroxylase
EC 1.14.13.182 2-heptyl-3-hydroxy-4(1H)-quinolone synthase
EC 1.14.13.183 transferred now EC 1.14.14.120
EC 1.14.13.184 transferred now EC 1.14.14.121
EC 1.14.13.185 transferred now EC 1.14.15.33
EC 1.14.13.186 transferred now EC 1.14.15.34
EC 1.14.13.187 L-evernosamine nitrososynthase
EC 1.14.13.188 transferred now EC 1.14.15.35
EC 1.14.13.189 5-methyl-1-naphthoate 3-hydroxylase
EC 1.14.13.190 ferruginol synthase
EC 1.14.13.190 transferred now EC 1.14.14.175
EC 1.14.13.191 transferred now EC 1.14.14.70
EC 1.14.13.192 transferred now EC 1.14.14.122
EC 1.14.13.193 transferred now EC 1.14.14.123
EC 1.14.13.194 transferred now EC 1.14.14.78
EC 1.14.13.195 L-ornithine N5-monooxygenase (NADPH)
EC 1.14.13.196 L-ornithine N5-monooxygenase [NAD(P)H]
EC 1.14.13.197 transferred now EC 1.14.14.124
EC 1.14.13.198 transferred now EC 1.14.14.125
EC 1.14.13.199 transferred now EC 1.14.14.79
EC 1.14.13.200 tetracenomycin A2 monooxygenase-dioxygenase
EC 1.14.13.201 transferred now EC 1.14.14.126
EC 1.14.13.202 transferred now EC 1.14.14.127
EC 1.14.13.203 transferred now EC 1.14.14.128
EC 1.14.13.204 transferred now EC 1.14.14.129
EC 1.14.13.205 transferred now EC 1.14.14.80
EC 1.14.13.206 transferred now EC 1.14.14.130
EC 1.14.13.207 transferred now EC 1.14.14.31
EC 1.14.13.208 benzoyl-CoA 2,3-epoxidase
EC 1.14.13.209 salicyloyl-CoA 5-hydroxylase
EC 1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
EC 1.14.13.211 rifampicin monooxygenase
EC 1.14.13.212 1,3,7-trimethyluric acid 5-monooxygenase
EC 1.14.13.213 transferred now EC 1.14.14.131
EC 1.14.13.214 transferred now EC 1.14.14.132
EC 1.14.13.215 protoasukamycin 4-monooxygenase
EC 1.14.13.216 asperlicin C monooxygenase
EC 1.14.13.217 protodeoxyviolaceinate monooxygenase
EC 1.14.13.218 5-methylphenazine-1-carboxylate 1-monooxygenase
EC 1.14.13.219 resorcinol 4-hydroxylase (NADPH)
EC 1.14.13.220 resorcinol 4-hydroxylase (NADH)
EC 1.14.13.221 transferred now EC 1.14.15.28
EC 1.14.13.222 aurachin C monooxygenase/isomerase
EC 1.14.13.223 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase
EC 1.14.13.224 violacein synthase
EC 1.14.13.225 F-actin monooxygenase
EC 1.14.13.226 acetone monooxygenase (methylacetate-forming)
EC 1.14.13.227 propane 2-monooxygenase
EC 1.14.13.228 jasmonic acid 12-hydroxylase
EC 1.14.13.229 tert-butyl alcohol monooxygenase
EC 1.14.13.230 butane monooxygenase (soluble)
EC 1.14.13.231 tetracycline 11a-monooxygenase
EC 1.14.13.232 6-methylpretetramide 4-monooxygenase
EC 1.14.13.233 4-hydroxy-6-methylpretetramide 12a-monooxygenase
EC 1.14.13.234 5a,11a-dehydrotetracycline 5-monooxygenase
EC 1.14.13.235 indole-3-acetate monooxygenase
EC 1.14.13.236 toluene 4-monooxygenase
EC 1.14.13.237 aliphatic glucosinolate S-oxygenase
EC 1.14.13.238 dimethylamine monooxygenase
EC 1.14.13.239 carnitine monooxygenase
EC 1.14.13.240 2-polyprenylphenol 6-hydroxylase
EC 1.14.13.241 5-pyridoxate monooxygenase
EC 1.14.13.242 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase
EC 1.14.13.243 toluene 2-monooxygenase
EC 1.14.13.244 phenol 2-monooxygenase (NADH)
EC 1.14.13.245 assimilatory dimethylsulfide S-monooxygenase
EC 1.14.13.246 4β-methylsterol monooxygenase
EC 1.14.13.247 stachydrine N-demethylase
EC 1.14.13.248 L-aspartate N-monooxygenase (nitrosuccinate-forming)
EC 1.14.13.249 3-amino-4-hydroxybenzoate 2-monooxygenase
EC 1.14.13.250 nitrosourea synthase
EC 1.14.13.251 glycine betaine monooxygenase
EC 1.14.13.252 putrescine N-hydroxylase
EC 1.14.13.253 3-demethoxyubiquinone 3-hydroxylase (NADH)
EC 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
EC 1.14.14.1 unspecific monooxygenase
EC 1.14.14.2 deleted, included in EC 1.14.14.1
EC 1.14.14.3 bacterial luciferase
EC 1.14.14.4 deleted, identical to EC 1.14.15.7
EC 1.14.14.5 alkanesulfonate monooxygenase
EC 1.14.14.6 transferred now EC 1.14.13.111
EC 1.14.14.7 transferred now EC 1.14.19.9
EC 1.14.14.8 anthranilate 3-monooxygenase (FAD)
EC 1.14.14.9 4-hydroxyphenylacetate 3-monooxygenase
EC 1.14.14.10 nitrilotriacetate monooxygenase
EC 1.14.14.11 styrene monooxygenase
EC 1.14.14.12 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione monooxygenase
EC 1.14.14.13 4-(L-γ-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase
EC 1.14.14.14 aromatase
EC 1.14.14.15 (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase
EC 1.14.14.16 steroid 21-monooxygenase
EC 1.14.14.17 squalene monooxygenase
EC 1.14.14.18 heme oxygenase (biliverdin-producing)
EC 1.14.14.19 steroid 17α-monooxygenase
EC 1.14.14.20 phenol 2-monooxygenase (FADH2)
EC 1.14.14.21 dibenzothiophene monooxygenase
EC 1.14.14.22 dibenzothiophene sulfone monooxygenase
EC 1.14.14.23 cholesterol 7α-monooxygenase
EC 1.14.14.24 vitamin D 25-hydroxylase
EC 1.14.14.25 cholesterol 24-hydroxylase
EC 1.14.14.26 24-hydroxycholesterol 7α-hydroxylase
EC 1.14.14.27 resorcinol 4-hydroxylase (FADH2)
EC 1.14.14.28 long-chain alkane monooxygenase
EC 1.14.14.29 25/26-hydroxycholesterol 7α-hydroxylase
EC 1.14.14.30 isobutylamine N-monooxygenase
EC 1.14.14.31 ipsdienol synthase
EC 1.14.14.32 17α-hydroxyprogesterone deacetylase
EC 1.14.14.33 ethylenediaminetetraacetate monooxygenase
EC 1.14.14.34 methanesulfonate monooxygenase (FMNH2)
EC 1.14.14.35 dimethylsulfone monooxygenase
EC 1.14.14.36 tyrosine N-monooxygenase
EC 1.14.14.37 4-hydroxyphenylacetaldehyde oxime monooxygenase
EC 1.14.14.38 valine N-monooxygenase
EC 1.14.14.39 isoleucine N-monooxygenase
EC 1.14.14.40 phenylalanine N-monooxygenase
EC 1.14.14.41 (E)-2-methylbutanal oxime monooxygenase
EC 1.14.14.42 homomethionine N-monooxygenase
EC 1.14.14.43 (methylthio)alkanaldoxime N-monooxygenase
EC 1.14.14.44 phenylacetaldehyde oxime monooxygenase
EC 1.14.14.45 aromatic aldoxime N-monooxygenase
EC 1.14.14.46 pimeloyl-[acyl-carrier protein] synthase
EC 1.14.14.47 nitric-oxide synthase (flavodoxin)
EC 1.14.14.48 jasmonoyl-L-amino acid 12-hydroxylase
EC 1.14.14.49 12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase
EC 1.14.14.50 tabersonine 3-oxygenase
EC 1.14.14.51 (S)-limonene 6-monooxygenase
EC 1.14.14.52 (S)-limonene 7-monooxygenase
EC 1.14.14.53 (R)-limonene 6-monooxygenase
EC 1.14.14.54 phenylacetate 2-hydroxylase
EC 1.14.14.55 quinine 3-monooxygenase
EC 1.14.14.56 1,8-cineole 2-exo-monooxygenase
EC 1.14.14.57 taurochenodeoxycholate 6α-hydroxylase
EC 1.14.14.58 trimethyltridecatetraene synthase
EC 1.14.14.59 dimethylnonatriene synthase
EC 1.14.14.60 ferruginol monooxygenase
EC 1.14.14.61 carnosic acid synthase
EC 1.14.14.62 salviol synthase
EC 1.14.14.63 β-amyrin 16β-monooxygenase
EC 1.14.14.64 β-amyrin 6β-monooxygenase
EC 1.14.14.65 sugiol synthase
EC 1.14.14.66 marmesin synthase
EC 1.14.14.67 11-hydroxysugiol 20-monooxygenase
EC 1.14.14.68 syn-pimaradiene 3-monooxygenase
EC 1.14.14.69 ent-cassadiene hydroxylase
EC 1.14.14.70 ent-sandaracopimaradiene 3-hydroxylase
EC 1.14.14.71 cucurbitadienol 11-hydroxylase
EC 1.14.14.72 drimenol monooxygenase
EC 1.14.14.73 albendazole monooxygenase (sulfoxide-forming)
EC 1.14.14.74 albendazole monooxygenase (hydroxylating)
EC 1.14.14.75 fenbendazole monooxygenase (4'-hydroxylating)
EC 1.14.14.76 ent-isokaurene C2/C3-hydroxylase
EC 1.14.14.77 phenylacetonitrile α-monooxygenase
EC 1.14.14.78 phylloquinone ω-hydroxylase
EC 1.14.14.79 docosahexaenoic acid ω-hydroxylase
EC 1.14.14.80 long-chain fatty acid ω-monooxygenase
EC 1.14.14.81 flavanoid 3',5'-hydroxylase
EC 1.14.14.82 flavonoid 3'-monooxygenase
EC 1.14.14.83 geraniol 8-hydroxylase
EC 1.14.14.84 linalool 8-monooxygenase
EC 1.14.14.85 7-deoxyloganin 7-hydroxylase
EC 1.14.14.86 ent-kaurene monooxygenase
EC 1.14.14.87 2-hydroxyisoflavanone synthase
EC 1.14.14.88 isoflavone 3'-hydroxylase
EC 1.14.14.89 4'-methoxyisoflavone 2'-hydroxylase
EC 1.14.14.90 isoflavone 2'-hydroxylase
EC 1.14.14.91 trans-cinnamate 4-monooxygenase
EC 1.14.14.92 benzoate 4-monooxygenase
EC 1.14.14.93 3,9-dihydroxypterocarpan 6a-monooxygenase
EC 1.14.14.94 leukotriene-B4 20-monooxygenase
EC 1.14.14.95 germacrene A hydroxylase
EC 1.14.14.96 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
EC 1.14.14.97 methyltetrahydroprotoberberine 14-monooxygenase
EC 1.14.14.98 protopine 6-monooxygenase
EC 1.14.14.99 (S)-limonene 3-monooxygenase
EC 1.14.14.100 dihydrosanguinarine 10-monooxygenase
EC 1.14.14.101 dihydrochelirubine 12-monooxygenase
EC 1.14.14.102 N-methylcoclaurine 3'-monooxygenase
EC 1.14.14.103 tabersonine 16-hydroxylase
EC 1.14.14.104 vinorine hydroxylase
EC 1.14.14.105 taxane 10β-hydroxylase
EC 1.14.14.106 taxane 13α-hydroxylase
EC 1.14.14.107 ent-kaurenoic acid monooxygenase
EC 1.14.14.108 2,5-diketocamphane 1,2-monooxygenase
EC 1.14.14.109 3-hydroxyindolin-2-one monooxygenase
EC 1.14.14.110 2-hydroxy-1,4-benzoxazin-3-one monooxygenase
EC 1.14.14.111 9β-pimara-7,15-diene oxidase
EC 1.14.14.112 ent-cassa-12,15-diene 11-hydroxylase
EC 1.14.14.113 α-humulene 10-hydroxylase
EC 1.14.14.114 amorpha-4,11-diene 12-monooxygenase
EC 1.14.14.115 11-oxo-β-amyrin 30-oxidase
EC 1.14.14.116 averantin hydroxylase
EC 1.14.14.117 aflatoxin B synthase
EC 1.14.14.118 tryprostatin B 6-hydroxylase
EC 1.14.14.119 fumitremorgin C monooxygenase
EC 1.14.14.120 dammarenediol 12-hydroxylase
EC 1.14.14.121 protopanaxadiol 6-hydroxylase
EC 1.14.14.122 oryzalexin E synthase
EC 1.14.14.123 oryzalexin D synthase
EC 1.14.14.124 dihydromonacolin L hydroxylase
EC 1.14.14.125 monacolin L hydroxylase
EC 1.14.14.126 β-amyrin 28-monooxygenase
EC 1.14.14.127 methyl farnesoate epoxidase
EC 1.14.14.128 farnesoate epoxidase
EC 1.14.14.129 long-chain acyl-CoA ω-monooxygenase
EC 1.14.14.130 laurate 7-monooxygenase
EC 1.14.14.131 bursehernin 5'-monooxygenase
EC 1.14.14.132 (–)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase
EC 1.14.14.133 1,8-cineole 2-endo-monooxygenase
EC 1.14.14.134 β-amyrin 24-hydroxylase
EC 1.14.14.135 glyceollin synthase
EC 1.14.14.136 deoxysarpagine hydroxylase
EC 1.14.14.137 (+)-abscisic acid 8'-hydroxylase
EC 1.14.14.138 lithocholate 6β-hydroxylase
EC 1.14.14.139 5β-cholestane-3α,7α-diol 12α-hydroxylase
EC 1.14.14.140 transferred now EC 1.14.14.162
EC 1.14.14.141 psoralen synthase
EC 1.14.14.142 8-dimethylallylnaringenin 2'-hydroxylase
EC 1.14.14.143 (+)-menthofuran synthase
EC 1.14.14.144 abieta-7,13-diene hydroxylase
EC 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase
EC 1.14.14.146 geranylgeraniol 18-hydroxylase
EC 1.14.14.147 22α-hydroxysteroid 23-monooxygenase
EC 1.14.14.148 angelicin synthase
EC 1.14.14.149 5-epiaristolochene 1,3-dihydroxylase
EC 1.14.14.150 costunolide synthase
EC 1.14.14.151 premnaspirodiene oxygenase
EC 1.14.14.152 β-amyrin 11-oxidase
EC 1.14.14.153 indole-2-monooxygenase
EC 1.14.14.154 sterol 14α-demethylase
EC 1.14.14.155 3,6-diketocamphane 1,2-monooxygenase
EC 1.14.14.156 tryptophan N-monooxygenase
EC 1.14.14.157 indolin-2-one monooxygenase
EC 1.14.14.158 carotenoid ε hydroxylase
EC 1.14.14.159 dolabradiene monooxygenase
EC 1.14.14.160 zealexin A1 synthase
EC 1.14.14.161 nepetalactol monooxygenase
EC 1.14.14.162 flavanone 2-hydroxylase
EC 1.14.14.163 (S)-1-hydroxy-N-methylcanadine 13-hydroxylase
EC 1.14.14.164 fraxetin 5-hydroxylase
EC 1.14.14.165 indole-3-carbonyl nitrile 4-hydroxylase
EC 1.14.14.166 (S)-N-methylcanadine 1-hydroxylase
EC 1.14.14.167 (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase
EC 1.14.14.168 germacrene A acid 8β-hydroxylase
EC 1.14.14.169 eupatolide synthase
EC 1.14.14.170 8-epi-inunolide synthase
EC 1.14.14.171 β-amyrin 16α-hydroxylase
EC 1.14.14.172 3,5,6-trichloropyridin-2-ol monooxygenase
EC 1.14.14.173 2,4,6-trichlorophenol monooxygenase
EC 1.14.14.174 geranylhydroquinone 3''-hydroxylase
EC 1.14.14.175 ferruginol synthase
EC 1.14.14.176 taxadiene 5α-hydroxylase
EC 1.14.14.177 ultra-long-chain fatty acid ω-hydroxylase
EC 1.14.14.178 steroid 22S-hydroxylase
EC 1.14.14.179 brassinosteroid6-oxygenase
EC 1.14.14.180 brassinolide synthase
EC 1.14.14.181 sulfoquinovose monooxygenase
EC 1.14.14.182 taxoid 7β-hydroxylase
EC 1.14.14.183 taxoid 2α-hydroxylase
EC 1.14.14.184 5-dehydro-6-demethoxyfumagillol synthase
EC 1.14.14.185 taxane 9α-hydroxylase
EC 1.14.14.186 tryptamine 5-hydroxylase
EC 1.14.14.187 rhazimal synthase
EC 1.14.14.188 norfluorocurarine 18-hydroxylase
EC 1.14.14.189 strychnine 10-hydroxylase
EC 1.14.14.190 β-colubrine 11-hydroxylase
EC 1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
EC 1.14.15.1 camphor 5-monooxygenase
EC 1.14.15.2 transferred now EC 1.14.13.162
EC 1.14.15.3 alkane 1-monooxygenase
EC 1.14.15.4 steroid 11β-monooxygenase
EC 1.14.15.5 corticosterone 18-monooxygenase
EC 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
EC 1.14.15.7 choline monooxygenase
EC 1.14.15.8 steroid 15β-monooxygenase
EC 1.14.15.9 spheroidene monooxygenase
EC 1.14.15.10 (+)-camphor 6-endo-hydroxylase
EC 1.14.15.11 pentalenic acid synthase
EC 1.14.15.12 transferred, now EC 1.14.14.46
EC 1.14.15.13 pulcherriminic acid synthase
EC 1.14.15.14 methyl-branched lipid ω-hydroxylase
EC 1.14.15.15 cholestanetriol 26-monooxygenase
EC 1.14.15.16 vitamin D3 24-hydroxylase
EC 1.14.15.17 pheophorbide-a oxygenase
EC 1.14.15.18 calcidiol 1-monooxygenase
EC 1.14.15.19 C-19 steroid 1α-hydroxylase
EC 1.14.15.20 heme oxygenase (biliverdin-producing, ferredoxin)
EC 1.14.15.21 zeaxanthin epoxidase
EC 1.14.15.22 vitamin D 1,25-hydroxylase
EC 1.14.15.23 chloroacetanilide N-alkylformylase
EC 1.14.15.24 β-carotene 3-hydroxylase
EC 1.14.15.25 p-cymene methyl-monooxygenase
EC 1.14.15.26 toluene methyl-monooxygenase
EC 1.14.15.27 β-dihydromenaquinone-9 ω-hydroxylase
EC 1.14.15.28 cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]
EC 1.14.15.29 cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]
EC 1.14.15.30 3-ketosteroid 9α-monooxygenase
EC 1.14.15.31 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase
EC 1.14.15.32 pentalenene oxygenase
EC 1.14.15.33 pikromycin synthase
EC 1.14.15.34 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
EC 1.14.15.35 6-deoxyerythronolide B hydroxylase
EC 1.14.15.36 sterol 14α-demethylase (ferredoxin)
EC 1.14.15.37 luteothin monooxygenase
EC 1.14.15.38 N,N-dimethyl phenylurea N-demethylase
EC 1.14.15.39 epi-isozizaene 5-monooxygenase
EC 1.14.15.40 cyclohexane-1-carboxylate 4-trans-hydroxylase
EC 1.14.15.41 L-tryptophan 4-nitrase
EC 1.14.15.42 L-tyrosine 3-nitrase
EC 1.14.15.43 nocardicin C N-oxygenase
EC 1.14.15.44 3-dehydro-2,22-dideoxyecdysone 22-hydroxylase
EC 1.14.15.45 4-hydroxy-3-polyprenylbenzoate 5-hydroxylase
EC 1.14.15.46 2-methoxy-6-polyprenylphenol 4-hydroxylase
EC 1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen
EC 1.14.16.1 phenylalanine 4-monooxygenase
EC 1.14.16.2 tyrosine 3-monooxygenase
EC 1.14.16.3 deleted
EC 1.14.16.4 tryptophan 5-monooxygenase
EC 1.14.16.5 alkylglycerol monooxygenase
EC 1.14.16.6 mandelate 4-monooxygenase
EC 1.14.16.7 phenylalanine 3-monooxygenase
EC 1.14.17 With reduced ascorbate as one donor, and incorporation of one atom of oxygen
EC 1.14.17.1 dopamine β-monooxygenase
EC 1.14.17.2 deleted, included in EC 1.14.18.1
EC 1.14.17.3 peptidylglycine monooxygenase
EC 1.14.17.4 aminocyclopropanecarboxylate oxidase
EC 1.14.18 With another compound as one donor, and incorporation of one atom of oxygen
EC 1.14.18.1 tyrosinase
EC 1.14.18.2 CMP-N-acetylneuraminate monooxygenase
EC 1.14.18.3 methane monooxygenase (particulate)
EC 1.14.18.4 phosphatidylcholine 12-monooxygenase
EC 1.14.18.5 sphingolipid C4-monooxygenase
EC 1.14.18.6 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase
EC 1.14.18.7 dihydroceramide fatty acyl 2-hydroxylase
EC 1.14.18.8 transferred now included with EC 1.14.14.139
EC 1.14.18.9 4α-methylsterol monooxygenase
EC 1.14.18.10 plant 4,4-dimethylsterol C-4α-methyl-monooxygenase
EC 1.14.18.11 plant 4α-monomethylsterol monooxygenase
EC 1.14.18.12 2-hydroxy fatty acid dioxygenase
EC 1.14.19 With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
EC 1.14.19.1 stearoyl-CoA 9-desaturase
EC 1.14.19.2 stearoyl-[acyl-carrier-protein] 9-desaturase
EC 1.14.19.3 acyl-CoA 6-desaturase
EC 1.14.19.4 acyl-lipid (11-3)-desaturase
EC 1.14.19.5 acyl-CoA 11-(Z)-desaturase
EC 1.14.19.6 acyl-CoA (9+3)-desaturase
EC 1.14.19.7 transferred now EC 1.11.1.23
EC 1.14.19.8 pentalenolactone synthase
EC 1.14.19.9 tryptophan 7-halogenase
EC 1.14.19.10 icosanoyl-CoA 5-desaturase
EC 1.14.19.11 palmitoyl-[acyl-carrier-protein] 4-desaturase
EC 1.14.19.12 acyl-lipid ω-(9-4) desaturase
EC 1.14.19.13 acyl-CoA 15-desaturase
EC 1.14.19.14 linoleoyl-lipid Δ9 conjugase
EC 1.14.19.15 (11Z)-hexadec-11-enoyl-CoA conjugase
EC 1.14.19.16 linoleoyl-lipid Δ12 conjugase (11E,13Z-forming)
EC 1.14.19.17 sphingolipid 4-desaturase
EC 1.14.19.18 sphingolipid 8-(E)-desaturase
EC 1.14.19.19 sphingolipid 10-desaturase
EC 1.14.19.20 Δ7-sterol 5(6)-desaturase
EC 1.14.19.21 cholesterol 7-desaturase
EC 1.14.19.22 acyl-lipid ω-6 desaturase (cytochrome b5)
EC 1.14.19.23 acyl-lipid (n+3)-(Z)-desaturase (ferredoxin)
EC 1.14.19.24 acyl-CoA 11-(E)-desaturase
EC 1.14.19.25 acyl-lipid ω-3 desaturase (cytochrome b5)
EC 1.14.19.26 acyl-[acyl-carrier-protein] 6-desaturase
EC 1.14.19.27 sn-2 palmitoyl-lipid 9-desaturase
EC 1.14.19.28 sn-1 stearoyl-lipid 9-desaturase
EC 1.14.19.29 sphingolipid 8-(E/Z)-desaturase
EC 1.14.19.30 acyl-lipid (8-3)-desaturase
EC 1.14.19.31 acyl-lipid (7-3)-desaturase
EC 1.14.19.32 palmitoyl-CoA 14-(E/Z)-desaturase
EC 1.14.19.33 Δ12 acyl-lipid conjugase (11E,13E-forming)
EC 1.14.19.34 acyl-lipid (9+3)-(E)-desaturase
EC 1.14.19.35 sn-2 acyl-lipid ω-3 desaturase (ferredoxin)
EC 1.14.19.36 sn-1 acyl-lipid ω-3 desaturase (ferredoxin)
EC 1.14.19.37 acyl-CoA 5-desaturase
EC 1.14.19.38 acyl-lipid Δ6-acetylenase
EC 1.14.19.39 acyl-lipid Δ12-acetylenase
EC 1.14.19.40 hex-5-enoyl-[acyl-carrier protein] acetylenase
EC 1.14.19.41 sterol 22-desaturase
EC 1.14.19.42 palmitoyl-[glycerolipid] 7-desaturase
EC 1.14.19.43 palmitoyl-[glycerolipid] 3-(E)-desaturase
EC 1.14.19.44 acyl-CoA (8-3)-desaturase
EC 1.14.19.45 sn-1 oleoyl-lipid 12-desaturase
EC 1.14.19.46 sn-1 linoleoyl-lipid 6-desaturase
EC 1.14.19.47 acyl-lipid (9-3)-desaturase
EC 1.14.19.48 tert-amyl alcohol desaturase
EC 1.14.19.49 tetracycline 7-halogenase
EC 1.14.19.50 noroxomaritidine synthase
EC 1.14.19.51 (S)-corytuberine synthase
EC 1.14.19.52 camalexin synthase
EC 1.14.19.53 all-trans-retinol 3,4-desaturase
EC 1.14.19.54 1,2-dehydroreticuline synthase
EC 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
EC 1.14.19.56 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase
EC 1.14.19.57 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] brominase
EC 1.14.19.58 tryptophan 5-halogenase
EC 1.14.19.59 tryptophan 6-halogenase
EC 1.14.19.60 7-chloro-L-tryptophan 6-halogenase
EC 1.14.19.61 dihydrorhizobitoxine desaturase
EC 1.14.19.62 secologanin synthase
EC 1.14.19.63 pseudobaptigenin synthase
EC 1.14.19.64 (S)-stylopine synthase
EC 1.14.19.65 (S)-cheilanthifoline synthase
EC 1.14.19.66 berbamunine synthase
EC 1.14.19.67 salutaridine synthase
EC 1.14.19.68 (S)-canadine synthase
EC 1.14.19.69 biflaviolin synthase
EC 1.14.19.70 mycocyclosin synthase
EC 1.14.19.71 fumitremorgin C synthase
EC 1.14.19.72 (–)-pluviatolide synthase
EC 1.14.19.73 (S)-nandinine synthase
EC 1.14.19.74 (+)-piperitol/(+)-sesamin synthase
EC 1.14.19.75 very-long-chain acyl-lipid ω-9 desaturase
EC 1.14.19.76 flavone synthase II
EC 1.14.19.77 plasmanylethanolamine desaturase
EC 1.14.19.78 decanoyl-[acyl-carrier protein] acetylenase
EC 1.14.19.79 3β,22α-dihydroxysteroid 3-dehydrogenase
EC 1.14.19.80 (19E)-geissoschizine oxidase
EC 1.14.19.81 polyneuridine aldehyde synthase
EC 1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
EC 1.14.20.1 deacetoxycephalosporin-C synthase
EC 1.14.20.2 transferred now EC 1.14.11.59
EC 1.14.20.3 (5R)-carbapenem-3-carboxylate synthase
EC 1.14.20.4 anthocyanidin synthase
EC 1.14.20.5 flavone synthase I
EC 1.14.20.6 flavonol synthase
EC 1.14.20.7 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)
EC 1.14.20.8 (–)-deoxypodophyllotoxin synthase
EC 1.14.20.9 L-tyrosine isonitrile desaturase
EC 1.14.20.10 L-tyrosine isonitrile desaturase/decarboxylase
EC 1.14.20.11 3-[(Z)-2-isocyanoethenyl]-1H-indole synthase
EC 1.14.20.12 3-[(E)-2-isocyanoethenyl]-1H-indole synthase
EC 1.14.20.13 6β-hydroxyhyoscyamine epoxidase
EC 1.14.20.14 hapalindole-type alkaloid chlorinase
EC 1.14.20.15 L-threonyl-[L-threonyl-carrier protein] 4-chlorinase
EC 1.14.20.16 4α,5β-5,20-epoxytax-11-ene-4,9-diol 9-dehydrogenase
EC 1.14.21 With NADH or NADPH as one donor, and the other dehydrogenated
EC 1.14.21.1 transferred now EC 1.14.19.64
EC 1.14.21.2 transferred now EC 1.14.19.65
EC 1.14.21.3 transferred now EC 1.14.19.66
EC 1.14.21.4 transferred now EC 1.14.19.67
EC 1.14.21.5 transferred now EC 1.14.19.68
EC 1.14.21.6 transferred now EC 1.14.19.20
EC 1.14.21.7 transferred now EC 1.14.19.69
EC 1.14.21.8 transferred now EC 1.14.19.63
EC 1.14.21.9 transferred now EC 1.14.19.70
EC 1.14.21.10 transferred now EC 1.14.19.71
EC 1.14.21.11 transferred now EC 1.14.19.72
EC 1.14.21.12 transferred now EC 1.14.19.73
EC 1.14.99 Miscellaneous
EC 1.14.99.1 prostaglandin-endoperoxide synthase
EC 1.14.99.2 kynurenine 7,8-hydroxylase
EC 1.14.99.3 transferred now EC 1.14.14.18
EC 1.14.99.4 progesterone monooxygenase
EC 1.14.99.5 now EC 1.14.19.1
EC 1.14.99.6 now EC 1.14.19.2
EC 1.14.99.7 transferred now EC 1.14.13.132
EC 1.14.99.8 deleted, included in EC 1.14.14.1
EC 1.14.99.9 steroid 17α-monooxygenase
EC 1.14.99.9 transferred now EC 1.14.14.19
EC 1.14.99.10 transferred now EC 1.14.14.16
EC 1.14.99.11 estradiol 6β-monooxygenase
EC 1.14.99.12 4-androstene-3,17-dione monooxygenase
EC 1.14.99.13 now EC 1.14.13.23
EC 1.14.99.14 progesterone 11α-monooxygenase
EC 1.14.99.15 4-methoxybenzoate monooxygenase (O-demethylating)
EC 1.14.99.16 now EC 1.14.13.72
EC 1.14.99.17 now EC 1.14.16.5
EC 1.14.99.18 deleted
EC 1.14.99.19 transferred now EC 1.14.19.77
EC 1.14.99.20 phylloquinone monooxygenase (2,3-epoxidizing)
EC 1.14.99.21 Latia-luciferin monooxygenase (demethylating)
EC 1.14.99.22 ecdysone 20-monooxygenase
EC 1.14.99.23 3-hydroxybenzoate 2-monooxygenase
EC 1.14.99.24 steroid 9α-monooxygenase
EC 1.14.99.25 now EC 1.14.19.3
EC 1.14.99.26 2-hydroxypyridine 5-monooxygenase
EC 1.14.99.27 now EC 1.17.3.4
EC 1.14.99.28 transferred now EC 1.14.13.151
EC 1.14.99.29 deoxyhypusine monooxygenase
EC 1.14.99.30 transferred to EC 1.3.5.6
EC 1.14.99.31 transferred now EC 1.14.19.24
EC 1.14.99.32 transferred now EC 1.14.19.5
EC 1.14.99.33 transferred now EC 1.14.14.39
EC 1.14.99.34 monoprenyl isoflavone epoxidase
EC 1.14.99.35 thiophene-2-carbonyl-CoA monooxygenase
EC 1.14.99.36 transferred now EC 1.13.11.63
EC 1.14.99.37 transferred now EC 1.14.14.176
EC 1.14.99.38 cholesterol 25-hydroxylase
EC 1.14.99.39 ammonia monooxygenase
EC 1.14.99.40 transferred now EC 1.13.11.79
EC 1.14.99.41 transferred now EC 1.13.11.75
EC 1.14.99.42 transferred now EC 1.13.11.84
EC 1.14.99.43 transferred now EC 1.14.14.134
EC 1.14.99.44 diapolycopene oxygenase
EC 1.14.99.45 transferred, now EC 1.14.14.158
EC 1.14.99.46 pyrimidine oxygenase
EC 1.14.99.47 (+)-larreatricin hydroxylase
EC 1.14.99.48 heme oxygenase (staphylobilin-producing)
EC 1.14.99.49 transferred now EC 1.14.15.31
EC 1.14.99.50 γ-glutamyl hercynylcysteine S-oxide synthase
EC 1.14.99.51 transferred now EC 1.21.3.10
EC 1.14.99.52 L-cysteinyl-L-histidinylsulfoxide synthase
EC 1.14.99.53 lytic chitin monoxygenase
EC 1.14.99.54 lytic cellulose monooxygenase (C1-hydroxylating)
EC 1.14.99.55 lytic starch monooxygenase
EC 1.14.99.56 lytic cellulose monooxygenase (C4-dehydrogenating)
EC 1.14.99.57 heme oxygenase (mycobilin-producing)
EC 1.14.99.58 heme oxygenase (biliverdin-IX-β and δ-forming)
EC 1.14.99.59 tryptamine 4-monooxygenase
EC 1.14.99.60 3-demethoxyubiquinol 3-hydroxylase
EC 1.14.99.61 cyclooctat-9-en-7-ol 5-monooxygenase
EC 1.14.99.62 cyclooctatin synthase
EC 1.14.99.63 β-carotene 4-ketolase
EC 1.14.99.64 zeaxanthin 4-ketolase
EC 1.14.99.65 4-amino-L-phenylalanyl-[CmlP-peptidyl-carrier-protein] 3-hydroxylase
EC 1.14.99.66 [histone-H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase
EC 1.14.99.67 α-N-dichloroacetyl-p-aminophenylserinol N-oxygenase
EC 1.14.99.68 4-aminobenzoate N-oxygenase
EC 1.14.99.69 tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase
EC 1.15 Acting on superoxide as acceptor

EC 1.15.1.1 superoxide dismutase
EC 1.15.1.2 superoxide reductase
EC 1.16 Oxidizing metal ions

EC 1.16.1 With NAD+ or NADP+ as acceptor

EC 1.16.1.1 mercury(II) reductase
EC 1.16.1.2 diferric-transferrin reductase
EC 1.16.1.3 deleted
EC 1.16.1.4 deleted
EC 1.16.1.5 deleted
EC 1.16.1.6 cyanocobalamin reductase
EC 1.16.1.7 ferric-chelate reductase (NADH)
EC 1.16.1.8 [methionine synthase] reductase
EC 1.16.1.9 ferric-chelate reductase (NADPH)
EC 1.16.1.10 ferric-chelate reductase [NAD(P)H]
EC 1.16.3 With oxygen as acceptor

EC 1.16.3.1 ferroxidase
EC 1.16.3.2 bacterial non-heme ferritin
EC 1.16.3.3 manganese oxidase
EC 1.16.3.4 cuproxidase
EC 1.16.5 With quinone or similar compound as acceptor
EC 1.16.5.1 transferred now EC 7.2.1.3
EC 1.16.8 With flavin as acceptor

EC 1.16.8.1 deleted, now known to be catalysed by EC 2.5.1.17
EC 1.16.9 With a copper protein as acceptor

EC 1.16.9.1 iron:rusticyanin reductase
EC 1.16.98 With other, known, physiological acceptor
EC 1.16.98.1 transferred now EC 1.16.9.1
EC 1.16.99 With unknown physiological acceptor
EC 1.16.99.1 [Co(II) methylated amine-specific corrinoid protein] reductase
EC 1.17 Acting on CH or CH2 groups

EC 1.17.1 With NAD+ or NADP+ as acceptor

EC 1.17.1.1 CDP-4-dehydro-6-deoxyglucose reductase
EC 1.17.1.2 transferred now EC 1.17.7.4
EC 1.17.1.3 leucoanthocyanidin reductase EC 1.17.1.4 xanthine dehydrogenase
EC 1.17.1.5 nicotinate dehydrogenase
EC 1.17.1.6 now EC 1.17.99.5
EC 1.17.1.7 transferred, now EC 1.2.1.91
EC 1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase
EC 1.17.1.9 formate dehydrogenase
EC 1.17.1.10 formate dehydrogenase (NADP+)
EC 1.17.1.11 formate dehydrogenase (NAD+, ferredoxin)
EC 1.17.2 With a cytochrome as acceptor
EC 1.17.2.1 nicotinate dehydrogenase (cytochrome)
EC 1.17.2.2 lupanine 17-hydroxylase (cytochrome c)
EC 1.17.2.3 formate dehydrogenase (cytochrome-c-553)
EC 1.17.3 With oxygen as acceptor
EC 1.17.3.1 pteridine oxidase
EC 1.17.3.2 xanthine oxidase
EC 1.17.3.3 6-hydroxynicotinate dehydrogenase
EC 1.17.3.4 juglone 3-hydroxylase
EC 1.17.3.5 4-oxocyclohexanecarboxylate 2-dehydrogenase
EC 1.17.4 With a disulfide as acceptor
EC 1.17.4.1 ribonucleoside-diphosphate reductase
EC 1.17.4.2 ribonucleoside-triphosphate reductase (thioredoxin)
EC 1.17.4.3 transferred now EC 1.17.7.1
EC 1.17.4.4 vitamin-K-epoxide reductase (warfarin-sensitive)
EC 1.17.4.5 vitamin-K-epoxide reductase (warfarin-insensitive)
EC 1.17.5 With a quinone or similar compound as acceptor
EC 1.17.5.1 phenylacetyl-CoA dehydrogenase
EC 1.17.5.2 caffeine dehydrogenase
EC 1.17.5.3 formate dehydrogenase-N
EC 1.17.7 With an iron-sulfur protein as acceptor
EC 1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
EC 1.17.7.2 7-hydroxymethyl chlorophyll a reductase
EC 1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
EC 1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase
EC 1.17.8 With a flavin as acceptor
EC 1.17.8.1 hydroxysqualene dehydroxylase
EC 1.17.9 With a copper protein as acceptor
EC 1.17.9.1 4-methylphenol dehydrogenase (hydroxylating)
EC 1.17.9.2 (+)-pinoresinol hydroxylase
EC 1.17.98 With other, known, physiological acceptors
EC 1.17.98.1 deleted
EC 1.17.98.2 bacteriochlorophyllide c C-71-hydroxylase
EC 1.17.98.3 formate dehydrogenase (coenzyme F420)
EC 1.17.98.4 formate dehydrogenase (hydrogenase)
EC 1.17.99 With unknown physiological acceptors
EC 1.17.99.1 transferred now EC 1.17.9.71
EC 1.17.99.2 ethylbenzene hydroxylase
EC 1.17.99.3 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA 24-hydroxylase
EC 1.17.99.4 uracil/thymine dehydrogenase
EC 1.17.99.5 transferred, now EC 1.17.98.1
EC 1.17.99.6 epoxyqueuosine reductase
EC 1.17.99.7 transferred now EC 1.17.98.4
EC 1.17.99.8 limonene dehydrogenase
EC 1.17.99.9 heme a synthase
EC 1.17.99.10 steroid C-25 hydroxylase
EC 1.17.99.11 3-oxo-Δ1-steroid hydratase/dehydrogenase
EC 1.18 Acting on iron-sulfur proteins as donors

EC 1.18.1 With NAD+ or NADP+ as acceptor

EC 1.18.1.1 rubredoxin—NAD+ reductase
EC 1.18.1.2 ferredoxin—NADP+ reductase
EC 1.18.1.3 ferredoxin—NAD+ reductase
EC 1.18.1.4 rubredoxin—NAD(P)+ reductase
EC 1.18.1.5 putidaredoxin—NAD+ reductase
EC 1.18.1.6 adrenodoxin-NADP+ reductase
EC 1.18.1.7 ferredoxin—NAD(P)+ reductase (naphthalene dioxygenase ferredoxin-specific)
EC 1.18.1.8 transferred, now EC 7.2.1.2
EC 1.18.3 With H+ as acceptor
EC 1.18.3.1 now EC 1.18.99.1
EC 1.18.6 With dinitrogen as acceptor
EC 1.18.6.1 nitrogenase
EC 1.18.6.2 vanadium-dependent nitrogenase
EC 1.18.96 With other, known, physiological acceptors
EC 1.18.96.1 now EC 1.15.1.2
EC 1.18.99 With H+ as acceptors
EC 1.18.99.1 now EC 1.12.7.2
EC 1.19 Acting on reduced flavodoxin as donor

EC 1.19.1 With NAD+ or NADP+ as acceptor

EC 1.19.1.1 flavodoxin—NADP+ reductase
EC 1.19.6 With dinitrogen as acceptor
EC 1.19.6.1 nitrogenase (flavodoxin)
EC 1.20. Acting on phosphorus or arsenic in donors

EC 1.20.1 Acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor

EC 1.20.1.1 phosphonate dehydrogenase
EC 1.20.2 With a cytochrome as acceptor
EC 1.20.2.1 arsenate reductase (cytochrome c)
EC 1.20.4 Acting on phosphorus or arsenic in donors, with disulfide as acceptor
EC 1.20.4.1 arsenate reductase (glutathione/glutaredoxin)
EC 1.20.4.2 methylarsonate reductase
EC 1.20.4.3 mycoredoxin
EC 1.20.4.4 arsenate reductase (thioredoxin)
EC 1.20.9 With a copper protein as acceptor
EC 1.20.9.1 arsenate reductase (azurin)
EC 1.20.98 With other, known, physiological acceptors
EC 1.20.98.1 transferred now EC 1.20.9.1
EC 1.20.99 With unknown physiological acceptors
EC 1.20.99.1 arsenate reductase (donor)
EC 1.21 Acting on X-H and Y-H to form an X-Y bond

EC 1.21.1 With NAD+ or NADP+ as acceptor

EC 1.21.1.1 iodotyrosine deiodinase
EC 1.21.1.2 2,4-dichlorobenzoyl-CoA reductase
EC 1.21.3 With oxygen as acceptor
EC 1.21.3.1 isopenicillin-N synthase
EC 1.21.3.2 columbamine oxidase
EC 1.21.3.3 reticuline oxidase
EC 1.21.3.4 sulochrin oxidase [(+)-bisdechlorogeodin-forming]
EC 1.21.3.5 sulochrin oxidase [(–)-bisdechlorogeodin-forming]
EC 1.21.3.6 aureusidin synthase
EC 1.21.3.7 tetrahydrocannabinolic acid synthase
EC 1.21.3.8 cannabidiolic acid synthase
EC 1.21.3.9 transferred now EC 1.21.98.2
EC 1.21.3.10 hercynylcysteine S-oxide synthase
EC 1.21.3.11 precondylocarpine acetate synthase
EC 1.21.4 With a disulfide as acceptor
EC 1.21.4.1 D-proline reductase
EC 1.21.4.2 glycine reductase
EC 1.21.4.3 sarcosine reductase
EC 1.21.4.4 betaine reductase
EC 1.21.4.5 tetrachlorohydroquinone reductive dehalogenase
EC 1.21.98 With other, known, physiological acceptors
EC 1.21.98.1 cyclic dehypoxanthinyl futalosine synthase
EC 1.21.98.2 dichlorochromopyrrolate synthase
EC 1.21.98.3 anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
EC 1.21.98.4 PqqA peptide cyclase
EC 1.21.98.5 tetraether lipid synthase
EC 1.21.99 With unknown physiological acceptors
EC 1.21.99.1 β-cyclopiazonate dehydrogenase
EC 1.21.99.2 transferred, now EC 1.21.98.1
EC 1.21.99.3 thyroxine 5-deiodinase
EC 1.21.99.4 thyroxine 5'-deiodinase
EC 1.21.99.5 tetrachloroethene reductive dehalogenase
EC 1.22 Acting on halogen in donors

EC 1.22.1 With NAD+ or NADP+ as acceptor

EC 1.22.1.1 transferred now EC 1.21.1.1
EC 1.23 Reducing C-O-C group as acceptor

EC 1.23.1 With NADH or NADPH as donor

EC 1.23.1.1 (+)-pinoresinol reductase
EC 1.23.1.2 (+)-lariciresinol reductase
EC 1.23.1.3 (–)-pinoresinol reductase
EC 1.23.1.4 (–)-lariciresinol reductase
EC 1.23.5 With a quinone or related compound as acceptor
EC 1.23.5.1 violaxanthin de-epoxidase
EC 1.97 Other oxidoreductases

EC 1.97.1.1 chlorate reductase
EC 1.97.1.2 pyrogallol hydroxyltransferase
EC 1.97.1.3 transferred now EC 1.12.98.4
EC 1.97.1.4 [formate-C-acetyltransferase]-activating enzyme
EC 1.97.1.5 now EC 1.20.4.1
EC 1.97.1.6 now EC 1.20.99.1
EC 1.97.1.7 now EC 1.20.4.2
EC 1.97.1.8 transferred now EC 1.21.99.5
EC 1.97.1.9 selenate reductase (cytochrome c)
EC 1.97.1.10 transferred now EC 1.21.99.4
EC 1.97.1.11 transferred now EC 1.21.99.3
EC 1.97.1.12 photosystem I
EC 1.97.1.13 aliphatic sulfonate oxidoreductase
EC 1.97.1.14 selenate reductase (quinol)
EC 1.97.1.15 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate)
EC 1.98 Enzymes using H2 as reductant

EC 1.98.1.1 now EC 1.18.99.1
EC 1.99 Other enzymes using O2 as oxidant

EC 1.99.1 Hydroxylases (now EC 1.14)

EC 1.99.1.1 deleted, now EC 1.14.14.1
EC 1.99.1.2 deleted, now EC 1.14.16.1
EC 1.99.1.3 deleted
EC 1.99.1.4 deleted
EC 1.99.1.5 deleted, now EC 1.14.13.9
EC 1.99.1.6 deleted
EC 1.99.1.7 deleted, now EC 1.14.15.4
EC 1.99.1.8 deleted
EC 1.99.1.9 deleted, now EC 1.14.99.9
EC 1.99.1.10 deleted
EC 1.99.1.11 deleted, now EC 1.14.99.10
EC 1.99.1.12 deleted
EC 1.99.1.13 deleted, covered by EC 1.14.99.7 and EC 5.4.99.7
EC 1.99.1.14 deleted, now EC 1.13.11.27

EC 1.99.2 Oxygenases (now EC 1.13)

EC 1.99.2.1 deleted, now EC 1.13.11.12
EC 1.99.2.2 deleted, now EC 1.13.11.1
EC 1.99.2.3 deleted, now EC 1.13.11.3
EC 1.99.2.4 deleted, now EC 1.13.11.4
EC 1.99.2.5 deleted, now EC 1.13.11.5
EC 1.99.2.6 deleted, now EC 1.13.99.1

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