IUBMB Enzyme Nomenclature


Accepted name: 12-hydroxydihydrochelirubine 12-O-methyltransferase

Reaction: S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine = S-adenosyl-L-homocysteine + dihydromacarpine

For diagram click here.

Systematic name: S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase

Comments: this reaction is part of the pathway for synthesis of benzophenanthridine alkaloid macarpine in plants.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 158736-40-4


1. Kammerer, L., De-Eknamkul, W., Zenk, M.H. Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine in dihydromacarpine formation by Thalictrum bulgaricum. Phytochemistry 36 (1994) 1409-1416.

[EC created 1999]

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