IUBMB Enzyme Nomenclature


Accepted name: 16S rRNA (cytosine1407-C5)-methyltransferase

Reaction: S-adenosyl-L-methionine + cytosine1407 in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine1407 in 16S rRNA

Other name(s): RNA m5C methyltransferase YebU; RsmF; YebU

Systematic name: S-adenosyl-L-methionine:16S rRNA (cytosine1407-C5)-methyltransferase

Comments: The enzyme specifically methylates cytosine1407 at C5 in 16S rRNA.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:


1. Andersen, N.M. and Douthwaite, S. YebU is a m5C methyltransferase specific for 16 S rRNA nucleotide 1407. J. Mol. Biol. 359 (2006) 777-786. [PMID: 16678201]

2. Hallberg, B.M., Ericsson, U.B., Johnson, K.A., Andersen, N.M., Douthwaite, S., Nordlund, P., Beuscher, A.E., 4th and Erlandsen, H. The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain. J. Mol. Biol. 360 (2006) 774-787. [PMID: 16793063]

[EC created 2010]

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